Cell and gene therapy
Getting started guides
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A guide to biopharma solutions from Oxford Nanopore
This guide introduces Oxford Nanopore sequencing solutions for biopharma that can be applied from biomarker discovery through to final product quality control (QC) testing.
Most viewed
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A successor to Sanger: accurate, full-length, and haplotype-resolved amplicon sequencing with Oxford Nanopore
In this application note, we evaluate Oxford Nanopore sequencing for amplicon analysis using matched datasets generated with both Oxford Nanopore and Sanger sequencing.
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Oxford Nanopore sequencing solutions for cell and gene therapies
Discover how Oxford Nanopore technology can support the development of your cell, gene, and RNA therapies.
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Unlocking the biopharma development pipeline with Oxford Nanopore
Discover how a molecular sensing technology is transforming the drug development and commercialisation pipeline.
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Pharmacogenomic Oxford Nanopore sequencing of the Twist Alliance Long-Read PGx Panel
Discover how the Oxford Nanopore and Twist Bioscience pharmacogenomic research workflow delivers PGx sequencing without compromise.
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Oxford Nanopore sequencing solutions for quality control in biopharma
Discover the biopharma QC Test Packs available from Oxford Nanopore Technologies.
Workflow overviews
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Nanopore-only microbial isolate sequencing solution (NO-MISS): flexible, rapid bacterial and fungal isolate whole-genome sequencing
This end-to-end workflow provides a rapid solution for whole-genome Oxford Nanopore sequencing of bacterial and fungal isolates.
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Rapid and complete plasmid characterisation with Oxford Nanopore sequencing
This end-to-end workflow is a rapid method for complete, high-quality whole-plasmid characterisation.
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Real-time enrichment of a comprehensive pharmacogenomic panel with Oxford Nanopore sequencing
This end-to-end workflow introduces how to enrich a comprehensive panel of PGx targets with real-time targeted Oxford Nanopore sequencing.
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Rapid and scalable full-length amplicon validation with Oxford Nanopore sequencing
This end-to-end workflow introduces how to validate full-length amplicons with Oxford Nanopore sequencing.
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Oxford Nanopore sequencing of native adeno-associated virus vectors for quality control
This end-to-end workflow provides a simple method to characterise full-length, native AAV vectors for QC measures.
Featured resources
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Advanced analytics for biopharma using nanopore sequencing | LC26
Biologics encompass a diverse range of customizable agents (mRNAs, cell lines, and viral products) derived from living organisms. Both their evolution as well as their ever-expanding number of applications mark a transformative shift in modern medicine. Nevertheless, inherent risks, including potent
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Nanopore sequencing enables scalable, end-to-end quality control and capsid library profiling of recombinant AAV vectors | LC26
Recombinant adeno-associated viruses (rAAVs) are among the most widely used vectors for gene therapy, requiring stringent quality control to ensure vector integrity, safety, and therapeutic performance. Oxford Nanopore Technologies (ONT) sequencing enables unbiased, real-time analysis of native DNA
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Stepping into the future of nanopore protein sequencing | LC 25
BiographyJeff Nivala is a professor in the Paul G. Allen School of Computer Science & Engineering at the University of Washington in Seattle and co-director of the Molecular Information Systems Lab. His research focuses on developing molecular read/write technologies and proteomics. Jeff
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Implementation of sequencing in a regulated environment
Hear from three experts in implementing nanopore sequencing in regulated environments.
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Dorado update
An overview of the latest features in the Dorado basecalling software and what's coming up next.
Latest research
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AviNP-Seq: a blindspot-free single-molecule framework for unmasking AAV genome heterogeneity and determining packaging limits
Publication: AviNP-Seq: a blindspot-free single-molecule framework for unmasking AAV genome heterogeneity and determining packaging limits
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Third-generation nanopore sequencing for post-transplant chimerism monitoring
Publication: Third-generation nanopore sequencing for post-transplant chimerism monitoring
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De-risking RNA therapeutics with high-resolution sequencing
Watch on demand to learn how integrating sequencing-driven insights across development and manufacturing can reduce risk and strengthen confidence as RNA programs advance toward the clinic.
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Analytical assessment of sgRNA impurities and their impact on functional performance
Publication: Analytical assessment of sgRNA impurities and their impact on functional performance
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Masterclass: How to sequence full-length plasmids in your own lab | LC25
Discover how to perform on-demand sequencing of full-length plasmids securely in your own lab, using a complete sample-to-answer workflow with Oxford Nanopore technology.
In this masterclass, you will learn:
How Oxford Nanopore sequencing delivers accurate, flexible, and secure plasmid c
