Our goal is to enable the analysis of anything, by anyone, anywhere.
We have developed a new generation of sensing technology that uses nanopores - nano-scale holes - embedded in high-tech electronics, to perform comprehensive molecular analyses.
Our first products sequence DNA and RNA. We offer the only sequencing technology to combine scalability from portable to ultra-high throughput formats with real-time data delivery and the ability to elucidate accurate, rich biological data through the analysis of short to ultra-long fragments of native DNA or RNA. The sensing platform has the potential to be adapted for the analysis of other types of molecules, for example proteins.View products
Use of the technology
The platform is used by scientific researchers to answer questions about the biology of people, plants, animals, pathogens and environments. It is also increasingly being used in ‘applied’ settings such as clinical diagnostics, epidemiology and food safety. It is our goal to enable users to answer a wide range of important biological questions that solve real-world challenges, whether in healthcare, epidemiology, environmental science, food and agriculture or education.Find out more
Nanopore sequencing, the only technology that offers scientific researchers:
- Sequence any DNA/RNA fragment length from short to ultra-long Characterise more genetic variation, versatile to broad applications
- Direct sequencing of native DNA/RNA Generate content-rich data, including methylation
- Data available in real time Rapid insights, and analyses that can respond to results in real time
- Scalable from portable devices to ultra-high throughput desktop devices Sequence anything, anywhere
- No capital investment required Accessible and cost effective
- Simple & rapid, or automated, library prep Easy to use and versatile
"we can detect allele-specific methylation using nanopore sequencing with high accuracy"
Henri van Kruistum, Wageningen University, NetherlandsWatch the talk
"gapless and telomere-to-telomere assembly of chromosome sequences is now possible"
Caroline Belser, University of Paris-Saclay, FranceRead the publication
"Nanopore sequencing can achieve high performance on 5mC detection in plants, even with low coverage of reads."
Peng Ni, Central South University, ChinaRead the publication
"the generation of ultra-long reads is a game-changer for assembling complex regions, composed of TEs, common in plant genomes."
Mathieu Rousseau-Gueutin, University of Rennes, FranceRead the publication
"To overcome the challenges of sequencing and assembling the even-larger genomes of lungfish we used long- and ultra-long-read Nanopore technology"
Axel Meyer, University of Konstanz, GermanyRead the blog
"Using nanopore sequencing data, we generated base level maps of the most complete human methylome ever produced"
Ariel Gershman, Johns Hopkins UniversityRead the publication
"Long reads improve genomic assemblies by spanning repetitive regions and structural variation within the genome"
Trent Prall, University of WisconsinRead the publication
"Long-read nanopore sequencing greatly illuminates the methylation landscape of young transposable elements in cancer"
Adam Ewing, University of QueenslandRead the publication
"The ability of nanopore sequencing to evaluate methylation from native DNA sequences obviated the need for bisulfite modification"
Thidathip Wongsurawat, University of Arkansas for Medical Sciences, USRead the publication
"We identified over 22,636 SVs per individual, three to five times more than those found in short-read sequencing data"
Doruk Beyter, deCODE geneticsRead the publication
"Targeted long-read sequencing … allowed us to simultaneously assay repeat length, sequence content, and methylation"
Danny Miller, University of Washington, USRead the publication
"ultra-long reads…profile patterns of methylation over repetitive regions that are often difficult to detect with short-read sequencing"
Karen Miga, University of California Santa Cruz, USRead the publication