Software downloads

Features

• DNA v5.0.0 Model Release - Transformer models with new 4mC/5mC model.
• Faster all-context modification calling for DNA models.
• Ability to perform optional system update when doing MinKNOW update.
• Live remote transfer moved to released.

Improvements

• Poly A tail length estimation on by default when running direct RNA (SQK-RNA004).
• Improved MinKNOW run recovery during device errors (interruptible protocols).
• Minor script updates - remove voltage flick during pore scan.
• Read integrity checks - data loss detection.
• Support for new kits - Direct RNA Sequencing Kit XL and Microbial Amplicon Barcoding Sequencing Kit 24 V14.
• Security updates - disabled developer API tokens.
• Improved read quality by trimming ends of blocked reads.
• Blocked unsupported combinations when running Run Until barcode coverage / alignment coverage.

Bug Fixes

• Fix for script crashes due to underlying system communication issues.
• Elimination of duplicate pause/resume actions which had caused the UI to freeze.
• Fix for hardware checks incorrectly reporting errors after passing.
• Always add filename_bam field to sequencing summary file.
• Fix for channel selection and Adaptive Sampling.
• When basecalling is off, raw reads are now output to the pod5 folder instead of pod5_skip.