Resource Centre
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High prevalence of reverse transcriptase inhibitors associated resistance mutations among people living with HIV on dolutegravir-based antiretroviral
- Virus
- AMR
- Infectious disease
- GridION
January 7 2025
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An improved rapid and sensitive long amplicon method for nanopore-based RSV whole genome sequencing
- Virus
- Infectious disease
- Amplicons
- MinION
January 7 2025
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Isoform-level discovery, quantification and fusion analysis from single-cell and spatial long-read RNA-seq data with Bambu-Clump
- Single cell
- RNA
- Transcriptomics
- Bioinformatics
- PromethION
January 1 2025
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Nanopore sequencing as a novel method of characterising anorexia nervosa risk loci
- Human genomics
- Neuroscience
- Metabolic
- Targeted
- Adaptive sampling
- Variant calling
December 31 2024
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Nanopore sequencing as a cutting-edge technology for medulloblastoma classification
- Cancer research
- Clinical research
- Flongle
- Methylation
- MinION
- Adaptive sampling
December 28 2024
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Rapid whole genome characterisation of antimicrobial-resistant pathogens using long-read sequencing to identify potential healthcare transmission
- Infectious disease
- Whole genome
- MinION
- Real-time
December 27 2024
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Verkko2: integrating proximity ligation data with long-read De Bruijn graphs for efficient telomere-to-telomere genome assembly, phasing, and scaffold
- Bioinformatics
- Long-read
- Phasing
December 26 2024
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Prognostic importance of direct assignment of parent-of-origin via long-read genome and epigenome sequencing in retinoblastoma
- Cancer research
- Phasing
- Adaptive sampling
- MinION
- Clinical research
December 26 2024
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MrHAMER2: high-accuracy long-read RNA sequencing to decode isoform-specific variation in viral transcripts during latency
- Virus
- Splice variation
- Long-read
- Isoforms
- RNA
- SNVs
December 22 2024
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The utility of long-read sequencing in diagnosing early-onset Parkinson's disease
- Human genomics
- Neuroscience
- Structural variation
- Phasing
- Adaptive sampling
- PromethION
December 19 2024
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Saliva microbiome profiling by full-gene 16S rRNA Oxford Nanopore Technology versus Illumina MiSeq sequencing
- 16S
- Microbiome
- GridION
- MinKNOW
- Bacteria
December 18 2024
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Long-read sequencing of hundreds of diverse brains provides insight into the impact of structural variation on gene expression and DNA methylation
- Human genomics
- Structural variation
- Methylation
- PromethION
December 18 2024
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Ultra-long sequencing for contiguous haplotype resolution of the human immunoglobulin heavy chain locus
- Human genomics
- Long-read
- Adaptive sampling
- Phasing
- Structural variation
- PromethION
December 17 2024
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mRNA m5C alteration in azacitidine demethylation treatment of acute myeloid leukaemia
- Cancer research
- Methylation
- mRNA
- GridION
- Epigenetics
December 17 2024
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Enhanced detection and genotyping of disease-associated tandem repeats using HMMSTR and targeted long-read sequencing
- Human genomics
- Neuroscience
- Cas enrichment
- Targeted
- MinION
- Scalable
December 16 2024
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Exploring how alternative splicing and gene isoforms influence disease
- Transcriptome
- Transcriptomics
- Single cell
- RNA
- Isoforms
December 12 2024
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Comparison of nanopore and classical sanger sequencing to identify mosquito bloodmeal hosts
- Infectious disease
- Animal
- MinION
- Flongle
December 12 2024
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Epitranscriptomic rRNA fingerprinting reveals tissue-of-origin and tumour-specific signatures
- Cancer research
- rRNA
- MinION
December 10 2024
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Rearrangements of viral and human genomes at human papillomavirus integration events and their allele-specific impacts on cancer genome regulation
- Cancer research
- Virus
- Methylation
- PromethION
December 5 2024
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Mycobacterium tuberculosis pseudo-outbreak due to laboratory cross-contamination: a molecular epidemiology outbreak investigation
- Infectious disease
- Clinical research
- Whole genome
December 5 2024