PromethION 2 Solo
If you are using the PromethION 2 Solo for the first time, download and install the latest version of the device software (MinKNOW) to the host computer or the GridION device to which you will connect the P2 Solo. The installation guide offers a walk-through. Any further software updates will pop up as notifications from the software user interface.
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Get the latest device software (MinKNOW) for PromethION 2 Solo
Using your P2 Solo with a GridION? Visit GridION page to update software
P2 Solo user manual
For more detailed advice on the device and its software, MinKNOW. Troubleshooting
Can I plug a P2 Solo into my P2 Integrated?
How do I connect my P2 Solo?
Can I use a USB-A cable or my own USB-C cable with the P2 Solo?
How many flow cells can I run on a GridION and P2 solo simultaneously?
What do the lights on my P2 Solo mean?
My P2 Solo is randomly disconnecting during my sequencing experiment
Can I plug a P2 Solo into a PromethION 24/48 Data Acquisition Unit as the compute?
Can I plug two P2 Solo devices into a GridION at the same time?
Can I use the MinION Mk1D USB-C cable with my P2 Solo?
Documentation and guides
Other software for PromethION 2 Solo
Our device software, MinKNOW, contains everything you need to use your sequencing device and perform basecalling. Explore other categories of software for standalone basecalling and post-basecalling analysis.

Standalone basecalling software
Basecalling software converts raw electrical signals into nucleotide sequences and provides additional data analysis tools. May be used as an alternative to MinKNOW’s built-in basecaller.

Data analysis software
Data analysis software, for example EPI2ME, processes genomic data beyond basecalling. It offers a range of diverse tools for investigations and techniques such as genome assembly, variant calling, and functional analysis.