Resource Centre
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Workflow overview: single-cell transcriptomics
- Single cell
- Transcriptome
- PromethION
- Cancer research
- Clinical research
- cDNA
February 20 2024
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Integrating 10x Genomics single-cell and spatial profiling with Oxford Nanopore long-read sequencing
- Single cell
- Webinar
- Human genomics
January 19 2024
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Core lab webinar series: New dimensions of biology revealed by full-length sequencing of single-cell and spatial assays
- Single cell
- Long-read
- PromethION
- cDNA
July 3 2023
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Untangling heterogeneity in DNA replication with nanopore sequencing
- Single cell
- London Calling
- Epigenetics
- Raw data
- Basecalling
- Whole genome
May 29 2019
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Uncovering RNA splicing’s cell-specific impact on clonal blood disorders with GoT-Splice
- Single cell
- Human genomics
- Transcriptome
April 8 2024
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Case study: ultra-rich nanopore data offers unprecedented insights into the transcriptomes of single cells
- Single cell
- RNA
- cDNA
- Human genomics
- Clinical research
- Transcriptome
January 17 2024
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Transposable element expression at unique loci in single cells with CELLO-seq
- Single cell
- Transcriptome
- Long-read
- Human genomics
- RNA
- cDNA
October 2 2020
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Taking your single-cell sequencing to new lengths with Oxford Nanopore
- Single cell
- Knowledge exchange
March 27 2024
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A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain
- Single cell
- Transcriptome
- PromethION
- Gene expression
- Isoforms
- Long-read
January 19 2021
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A single fiber view of the nucleosome organization in eukaryotic chromatin
- Single cell
- MinION
- Structural variation
- Methylation
November 22 2023
Single-cell transcriptomics unlocks cellular diversity using full-length cDNA sequencing, providing high-resolution analysis
- Single cell
- Cancer research
May 21 2024
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Single cell transcriptome sequencing on the Nanopore platform with ScNapBar
- Single cell
- GridION
- Long-read
- Human genomics
- Transcriptome
- Isoforms
October 16 2020
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Single-cell third-generation sequencing-based multi-omics uncovers gene expression changes governed by ecDNA and structural variants in cancer cells
- Single cell
- Structural variation
- PromethION
- Variant calling
- Cancer research
- Transcriptome
July 30 2023
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Single-cell rapid capture hybridization sequencing (scRaCH-seq) to reliably detect isoform usage and coding mutations in targeted genes at a single-cell level
- Single cell
- Cancer research
- Transcriptome
- Isoforms
January 30 2024
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Single-Cell Omics for Transcriptome CHaracterization (SCOTCH): isoform-level characterisation of gene expression through long-read single-cell RNA seq
- Single cell
- Bioinformatics
- Transcriptomics
April 30 2024
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Single-cell multiomics reveal the scale of multi-layered adaptations enabling CLL relapse during venetoclax therapy
- Single cell
- Transcriptome
- Cancer research
- Human genomics
- RNA
- cDNA
June 16 2022
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Single-cell multi-omics reveals elevated plasticity and stem-cell-like blasts relevant to the poor prognosis of KMT2A-rearranged leukemia
- Single cell
- Clinical research
- Cancer research
- Oncology
- Gene fusions
- RNA
December 7 2020
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Single-cell multi-omics defines the cell-type specific impact of splicing aberrations in human hematopoietic clonal outgrowths
- Single cell
- Cancer research
- Long-read
- Human genomics
- RNA
- cDNA
August 14 2023
Single-cell long-read targeted sequencing reveals transcriptional variation in ovarian cancer
- Single cell
- Cancer research
- Long-read
- PromethION
- Targeted
July 19 2023
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Single-cell long-read targeted sequencing reveals transcriptional variation in ovarian cancer
- Single cell
- Human genomics
- Cancer research
- MinION
- PromethION
- Guppy
August 12 2024