London Calling 2023: Nanopore sequencing of ctDNA — better than short read!

In this talk I will discuss the potential applications of nanopore ctDNA sequencing in developing a pan-cancer assay for detection and screening. Through this, I will demonstrate data that shows the detection of MDM2 copy number in sarcoma samples as well as very low input VAF samples. I will also give an overview of some of the technical challenges that have to be overcome with nanopore sequencing of ctDNA