Flexible, large-scale, direct DNA and RNA sequencing
Terabases of data
1 - 48 flow cells
Flexible, on-demand sequencing
High-performance compute
Analyse data in real time with 4x NVIDIA A100 GPUs
Up to 14 Tb data*
Population-scale sequencing
* Theoretical max output when system is run for 72 hours at 420 bases / second. Outputs may vary according to library type, run conditions, etc.
Why PromethION?
On-demand sequencing
Run up to 48 independently addressable, high-capacity PromethION Flow Cells.
Ultra-high throughput
Generate terabases of data — streamed in real time for immediate analysis.
Powerful compute
Alleviate data analysis bottlenecks.
Population-scale sequencing
Generate sub-$1,000 human genomes.
No capital cost
Pay just for consumables.
Interested in the P2?
PromethION 2 (P2) devices maintain the flexibility associated with the PromethION 24 and PromethION 48 devices, but in a compact, accessible form factor. They are designed for small to medium sized academic and research labs, as well as core labs and commercial service providers, – delivering the benefits of high-coverage nanopore sequencing to users with lower sample processing requirements (i.e. up to four full-length sequencing runs per week / or 200 flow cells per year).
Find out more
Specifications
Two PromethION models are available for high-throughput sequencing projects: the PromethION 24 (P24) and PromethION 48 (P48), respectively operating up to 24 and 48 flow cells at once. Both systems are deployed with the powerful PromethION A100 tower, utilising 4x NVIDIA A100 GPUs for real-time data handling.
Read length
Nanopores read the length of DNA or RNA presented to them — from short to ultra-long (longest >4 Mb)
Dimensions
Compact benchtop device with compute module
Sequencing module:
- Size: W 590 mm, H 190 mm, D 430 mm
- Weight: 28 kg
Compute module:
- Size: W 178 mm, H 440 mm, D 470 mm
- Weight: 25 kg
Up to 290 Gb per flow cell*
Total device yield as much as:
- Up to 7 Tb PromethION 24*
- Up to 14 Tb PromethION 48*
* Theoretical max output when system is run for 72 hours at 420 bases / second. Outputs may vary according to library type, run conditions, etc.
Suitable applications
- Larger genomes or projects
- Population-scale sequencing
- Highly multiplexed small genomes or targeted regions
- Whole transcriptomes (direct RNA or cDNA)
On demand
Sequence what you need, when you need it
- Run flow cells individually or together — no more sample batching
- Each flow cell has approximately six times the sequencing capacity of a MinION Flow Cell
- Run multiple DNA or RNA experiments at once
- Barcode for even more samples
- Suitable for high-throughput and service labs
Accessible
- No capital cost
- Small footprint — suitable for any lab
- Easy installation with comprehensive support
High-performance compute
Sequencing and analysis in one powerful device
- Latest generation CPU
- 4x NVIDIA A100 GPUs
- 60 TB SSD data storage
- 512 GB RAM
- Preloaded with Ubuntu OS and MinKNOW
Product documentation
PromethION IT Requirements
This checklist represents the minimal requirements for installing the PromethION in your institution.
192 KB
PDF
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