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MinION GridION PromethION Flongle VolTRAX
PromethION high-throughput nanopore sequencing device

Large-scale, long-read, direct DNA and RNA sequencing

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Terabases of data

1 - 48 flow cells

Flexible, on-demand sequencing

High-performance compute

Analyse data in real time

Up to 8 Tb data

Population-scale sequencing

Why PromethION?

PromethION high-throughput nanopore sequencing device

On-demand sequencing

Run up to 48 independently addressable, high-capacity PromethION Flow Cells.

Ultra-high throughput

Generate terabases of data — streamed in real time for immediate analysis.

Powerful compute

Alleviate data analysis bottlenecks.

Population-scale sequencing

Generate sub-$1,000 human genomes.

No capital cost

Pay just for consumables.

Nanopore Service Certification

Service provider certification is available for PromethION

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100 tomato genomes in 100 days

Researchers at Johns Hopkins University utilise PromethION to reveal substantial genomic variation between tomato plants, including a tandem duplication associated with higher fruit yield.

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Accessing the inaccessible human genome with long reads

Discover how Shafin and colleagues used PromethION to sequence 11 human cell lines in just 9 days.

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PromethION is available in two models: PromethION 24 (P24) and PromethION 48 (P48), which can respectively operate up to 24 and 48 flow cells at once.

Read length

Nanopores read the length of DNA or RNA presented to them — from short to ultra-long (longest >2 Mb)


Compact benchtop device with compute module

Sequencing module:

  • Size: W 590 mm, H 190 mm, D 430 mm
  • Weight: 28 kg

Compute module:

  • Size: W 178 mm, H 440 mm, D 470 mm
  • Weight: 25 kg

Up to 180 Gb per flow cell

Total device yield as much as:

  • 4 Tb PromethION 24
  • 8 Tb PromethION 48

Suitable applications

  • Larger genomes or projects
  • Population-scale sequencing
  • Highly multiplexed small genomes or targeted regions
  • Whole transcriptomes (direct RNA or cDNA)

On demand

Sequence what you need, when you need it

  • Run flow cells individually or together — no more sample batching
  • Each flow cell has approximately six times the sequencing capacity of a MinION Flow Cell
  • Run multiple DNA or RNA experiments at once
  • Barcode for even more samples
  • Suitable for high-throughput and service labs


  • No capital cost
  • Small footprint — suitable for any lab
  • Easy installation with comprehensive support

High-performance compute

Sequencing and analysis in one powerful device

  • Latest generation CPU for OS and orchestration
  • State-of-the-art basecall accelerators
  • 32 TB (P24) or 64 TB (P48) SSD data storage
  • 384 GB RAM
  • Instrument control and data analysis software

Simple workflow



Extract nucleic acid from your sample and prepare it for sequencing



Sequence your library on a device that suits your needs



Analyse your data from as soon as you start sequencing


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