Flexible, large-scale, direct DNA and RNA sequencing
Terabases of data
1 - 48 flow cells
Flexible, on-demand sequencing
High-performance compute
Analyse data in real time with 4 NVIDIA A-Series GPUs
Up to 14 Tb data*
Population-scale sequencing
* Theoretical max output when system is run for 72 hours at 420 bases / second. Outputs may vary according to library type, run conditions, etc.
Why PromethION?
On-demand sequencing
Run up to 48 independently addressable, high-capacity PromethION Flow Cells.
Ultra-high throughput
Generate terabases of data — streamed in real time for immediate analysis.
Powerful compute
Alleviate data analysis bottlenecks.
Population-scale sequencing
Generate sub-$1,000 human genomes.
No capital cost
Pay just for consumables.
Interested in the P2?
PromethION 2 (P2) devices maintain the flexibility associated with the PromethION 24 and PromethION 48 devices, but in a compact, accessible form factor. They are designed for small to medium sized academic and research labs, as well as core labs and commercial service providers, – delivering the benefits of high-coverage nanopore sequencing to users with lower sample processing requirements (i.e. up to four full-length sequencing runs per week / or 200 flow cells per year).
Find out more
Specifications
Two PromethION models are available for high-throughput sequencing projects: the PromethION 24 (P24) and PromethION 48 (P48), respectively operating up to 24 and 48 flow cells at once. Both systems are deployed with the powerful PromethION A-Series tower, utilising 4 NVIDIA A-Series GPUs for real-time data handling.
Read length
Nanopores read the length of DNA or RNA presented to them — from short to ultra-long (longest >4 Mb)
Dimensions
Compact benchtop device with compute module
Sequencing module:
- Size: W 590 mm, H 190 mm, D 430 mm
- Weight: 28 kg
Compute module:
- Size: W 178 mm, H 440 mm, D 470 mm
- Weight: 25 kg
Up to 290 Gb per flow cell*
Total device yield as much as:
- Up to 7 Tb PromethION 24*
- Up to 14 Tb PromethION 48*
* Theoretical max output when system is run for 72 hours at 420 bases / second. Outputs may vary according to library type, run conditions, etc.
Suitable applications
- Larger genomes or projects
- Population-scale sequencing
- Highly multiplexed small genomes or targeted regions
- Whole transcriptomes (direct RNA or cDNA)
On demand
Sequence what you need, when you need it
- Run flow cells individually or together — no more sample batching
- Each flow cell has approximately six times the sequencing capacity of a MinION Flow Cell
- Run multiple DNA or RNA experiments at once
- Barcode for even more samples
- Suitable for high-throughput and service labs
Accessible
- No capital cost
- Small footprint — suitable for any lab
- Easy installation with comprehensive support
High-performance compute
Sequencing and analysis in one powerful device
- Latest generation CPU
- 4 NVIDIA A-Series GPUs
- 60 TB SSD data storage
- 512 GB RAM
- Preloaded with Ubuntu OS and MinKNOW
Product documentation
PromethION IT Requirements
This checklist represents the minimal requirements for installing the PromethION in your institution.
192 KB
PDF
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