American Association of Cancer Research: Oxford Nanopore showcases transformative technology for accelerating oncology research

Meet our team of experts in booth #3053 and mark your calendars for our Spotlight Theatre presentations on Monday, 8th April at 12:30 PM PT.

Oxford Nanopore Technologies are looking forward to joining the cancer research community at this year’s American Association of Cancer Research (AACR) conference in San Diego, April 5th – 10th. While the genetic landscape of cancer is complex, with multiple genomic variants influencing and indicating disease, Oxford Nanopore’s streamlined, single-platform approach is accelerating precision oncology research. With native nanopore sequencing reads of any length, researchers can perform rapid and complete characterisation of cancer genomes and discover novel biomarkers, improving our understanding of oncology and treatment strategies.

Be sure to drop by booth #3053 throughout the event to meet our team of experts and hear more about how nanopore sequencing is accelerating oncology research.

Highlights include:

  • Spotlight Theatre presentations on Monday, 8th April, 12:30 PM (Spotlight Theatre B). See details and register interest below.
  • ‘Data for Breakfast’ – join us daily for coffee, pastries, and bioinformatics. All classes kick off at 9:30 AM at booth #3053.
  • Live demos – Discover how to enrich any cancer gene panel with adaptive sampling and learn how to characterise genomic and epigenomic variation between tumour-normal samples using long and native nanopore sequencing reads. See the daily schedule below.

Follow us on X @nanopore and LinkedIn for updates and news throughout the conference.

Exhibitor Spotlight Theatre

Monday, April 8th, 12:30 – 1:30 PM, Exhibition Hall Spotlight Theatre B

Native, PCR-free nanopore sequencing, with unrestricted read lengths, offers a unique view into cancer biology. This allows the identification of single nucleotide variants, structural variants, and epigenetic modifications on a haplotype level — from a single dataset.

In this session, we’ll explore how these technical benefits open a new window of understanding into cancer genomes. Presentations include:

  • Severus: accurate detection and characterisation of somatic structural variation in tumour genomes using long reads - Mikhail Kolmogorov & Ayse Keskus, National Cancer Institute, National Institutes of Health
  • Real-time genomic characterisation of paediatric acute leukaemia using adaptive sampling - Julie Geyer, University of North Carolina

Register here.

‘Data for Breakfast’ agenda

Monday, Tuesday, and Wednesday, 9:30 AM, booth #3053



Date and Time

Introduction to nanopore sequencing data analysis

Learn how to use the Oxford Nanopore human variation workflow to simultaneously phase genomic and epigenomic variants from data-rich nanopore sequencing reads.

Monday, April 8th, 9:30 AM

New Oxford Nanopore cancer bioinformatics tools and workflows

Hear about the advanced cancer bioinformatic tools available for nanopore sequencing data analysis. Perform somatic variant calling of single nucleotide variants (SNVs), structural variants (SVs), and differential methylation at the haplotype level from a single data set. Find out how to get full-length transcripts at the single-cell level.

Tuesday, April 9th, 9:30 AM

Get started with cancer bioinformatics using rich nanopore sequencing data

If you missed first two classes join us for this summary session covering basics of nanopore data analysis and cancer bioinformatics tools and workflows for genomic, epigenomic and transcriptomics analysis

Wednesday, April 10th, 9:30 AM

Live demonstrations in booth #3053



Date and Time

Flexible, PCR-free enrichment of a comprehensive hereditary cancer gene panel with long nanopore reads

Learn how to use adaptive sampling to enrich any cancer gene panel of interest. This on-device targeted sequencing method enables simultaneous genomic and epigenomic variant detection without need for PCR

Sunday, April 7th, 3:00 PM

Monday, April 8th, 11:30 AM

Tuesday, April 9th, 3:00 PM

Wednesday, April 10th, 11:30 AM

Simultaneous genomic and epigenomic cancer biomarker discovery with tumour-normal nanopore sequencing

Learn how to characterise genomic and epigenomic variation between tumour-normal samples using long and native nanopore sequencing reads

Monday, April 8th, 3:00 PM

Tuesday, April 9th, 11:30 AM

In the poster hall

Sunday, April 7th

1:30 PM – 5:00 PM

  • Translocation detection in cancer using low pass pore-c sequencing
  • Location: Section 17, 405/5
  • Presenter: Sergey Aganezov, Oxford Nanopore Technologies

Monday, April 8th

9:00 AM – 12:30 PM

  • Telomere dynamics in aging and cancer by nanopore long-read sequencing
  • Location: Section 13, 1639 / 9
  • Presenter: Tobias Schmidt, Salk Institute For Biological Studies
  • Methylation based phylogeny and timing in cancer
  • Location: Section 37, 2333 / 11
  • Presenter: Ignaty Leshchiner, Boston University
  • Benchmarking long- and short-read somatic structural variation callers using a multi-technology panel of six tumor/normal cell lines
  • Location: Section 37, 2338 / 16
  • Presenter: Asher Bryant, Center for Cancer Research, National Cancer Institute

1:30 PM – 5:00 PM

  • High resolution telomere measurements in human cancer and aging using long-read nanopore sequencing
  • Location: Section 53, LB185 / 1
  • Presenter: Steven Artandi, Stanford Cancer Institute
  • Solving the cancer mutation conundrum: A single cell, massively parallel approach for cancer mutation discovery, genome modelling and functional characterisation
  • Location: Section 14, 2928 / 3
  • Presenter: Hanlee P. Ji, Stanford University
  • Nanopore adaptive sampling detects nucleotide variants and improves large scale rearrangement characterisation for diagnosis of cancer predisposition
  • Location: Section 14, 2936 / 11
  • Presenter: Romain Boidot, Ctr. Georges-François Leclerc
  • Accurate detection of human papillomavirus breakpoints in cervical cancers using a novel library preparation strategy for nanopore sequencing technology
  • Location: Section 14, 2937 / 12
  • Presenter: Amrita Parida, Kasturba Medical College

Tuesday, April 9th

9:00 AM – 12:30 PM

  • A nanopore sequencing approach characterises cell-free DNA methylation-fragmentomics profiles indicative of breast cancer in a large cohort
  • Location: Section 36, 4920 / 16
  • Presenter: Xiangqi Bai, Stanford University School of Medicine
  • Detecting chromosomal copy number variations and point mutations in Glioma using a single assay; sparing tissue while significantly reducing testing time and cost
  • Location: Section 41, 5049 / 3
  • Presenter: Mashiat Mimosa, University of Toronto

1:30 PM – 5:00 PM

  • Haplotype-resolved analysis of cancer genomes and epigenomes using Oxford Nanopore sequencing
  • Location: Section 36, 6218 / 21
  • Presenter: Philipp Rescheneder, Oxford Nanopore Technologies
  • Native nanopore sequencing of multiple tumor sites reveals genetic and epigenetic intra-tumor heterogeneity in canine osteosarcoma
  • Location: Section 16, 5665 / 11
  • Presenter: Sergey Aganezov, Oxford Nanopore Technologies

Wednesday, April 10th

  • 9:00 AM – 12:30 PM
  • LongFuse: Detecting gene fusion transcripts from high throughput long-read single cell RNA sequencing data
  • Location: Section 35, 7418 / 13
  • Presenter: Cheng-Kai Shiau, Northwestern Univ. Feinberg School of Medicine
  • Identifying cell free DNA methylation signatures in cerebrospinal fluids for the early detection of brain metastasis in non-small cell lung cancer
  • Location: Section 15, 7019 / 19
  • Presenter: Tianqi Chen, Stanford University School of Medicine

For more information please see: cancer applications.