AACR Annual Meeting 2024
Event overview
The American Association for Cancer Research Annual Meeting highlights the best cancer science and medicine from institutions all over the world. Attendees are invited to stretch their boundaries, form collaborations, attend sessions outside their areas of expertise, and learn how to apply exciting new concepts, tools, and techniques to their own research.
Members of the Oxford Nanopore team will be on hand throughout the AACR Annual Meeting 2024. Please contact events@nanoporetech.com ahead of the event if you would like to arrange a meeting. You will be able to find us at booth 3053 throughout the conference - do stop by and say hello!
Please register below for our Spotlight Theater on Monday, April 8th at 12:30 PM. Hear leading researchers present their latest work demonstrating the advantages and novel applications of nanopore sequencing
See additional details below for our on-booth schedule of demos and Data for Breakfast.
Exhibitor Spotlight Theater
Accelerating precision oncology research with nanopore sequencing
Date: Monday, April 8th, 2024
Time: 12:30 PM – 1:30 PM PT
Location: Spotlight Theater B
Native, PCR-free nanopore sequencing, with unrestricted read lengths, offers a unique view into cancer biology. This allows the identification of single nucleotide variants, structural variants, and epigenetic modifications on a haplotype level — from a single dataset. In this session, we’ll explore how these technical benefits open up a new window of understanding into cancer genomes, featuring projects ranging from cancer whole-genome sequencing to cell-free DNA with methylation, and single-cell sequencing.
Speakers
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Severus: accurate detection and characterization of somatic structural variation in tumor genomes using long reads
Mikhail Kolmogorov, Principal Investigator, National Cancer Institute, National Institutes of Health
Before joining the Cancer Data Science Laboratory in January 2022, Mikhail was a postdoctoral fellow...
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Severus: accurate detection and characterization of somatic structural variation in tumor genomes using long reads
Ayse Keskus, Postdoctoral Fellow, National Cancer Institute, National Institutes of Health
Ayse Keskus received her PhD from Bilkent University in Turkey. She is a Postdoctoral Research Fello...
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Real-time genomic characterization of pediatric acute leukemia using adaptive sampling
Julie Geyer, Postdoctoral Research Associate, University of North Carolina at Chapel Hill School of Medicine
Julie is a postdoctoral researcher at UNC Chapel Hill in the School of Medicine studying cancer geno...
Spotlight Theater agenda
12:30 — 1:30 pm PT | Spotlight Theater | |
|---|---|---|
12:30 — 12:35 | Welcome and intro | Anna Dysko, Oxford Nanopore Technologies |
12:35 — 1:00 | Severus: accurate detection and characterization of somatic structural variation in tumor genomes using long reads | Mikhail Kolmogorov & Ayse Keskus, National Cancer Institute, National Institutes of Health |
1:00 — 1:25 | Real-time genomic characterization of pediatric acute leukemia using adaptive sampling | Julie Geyer, University of North Carolina |
1:25 — 1:30 | Closing | Anna Dysko, Oxford Nanopore Technologies |
Booth demos
Demo title | Description | Date |
|---|---|---|
Flexible, PCR-free enrichment of a comprehensive hereditary cancer gene panel with long nanopore reads | Learn how to use adaptive sampling to enrich any cancer gene panel of interest. This on-device targeted sequencing method enables simultaneous genomic and epigenomic variant detection without need for PCR | Sunday, April 7th - 3:00 pm Monday, April 8th - 11:30 am Tuesday, April 9th - 3:00 pm |
Simultaneous genomic and epigenomic cancer biomarker discovery with tumor-normal nanopore sequencing | Learn how to characterize genomic and epigenomic variation between tumor-normal samples using long and native nanopore sequencing reads | Monday, April 8th - 3:00 pm Tuesday, April 9th - 11:30 am Wednesday, April 10th - 11:30 am |
Data for Breakfast
Visit our booth for Data for Breakfast. The Oxford Nanopore team will present on the topics below. Coffee and pastries will be provided.
Monday, April 8th — 9:30 AM
Title: Introduction to nanopore sequencing data analysis
Description: Learn how to use the Oxford Nanopore human variation workflow to simultaneously phase genomic and epigenomic variants from data-rich nanopore sequencing reads.
Tuesday, April 9th — 9:30 AM
Title: New Oxford Nanopore cancer bioinformatics tools and workflows
Description: Hear about the advanced cancer bioinformatic tools available for nanopore sequencing data analysis. Perform somatic variant calling of SNVs, structural variants (SVs), and differential methylation at the haplotype level from a single data set. Find out how to get full-length transcripts at the single-cell level.
Wednesday, April 10th — 9:30 AM
Title: Get started with cancer bioinformatics using rich nanopore sequencing data
Description: If you missed first two classes join us for this summary session covering basics of nanopore data analysis and cancer bioinformatics tools and workflows for genomic, epigenomic and transcriptomics analysis
Posters featuring nanopore research
Late breaking research
High resolution telomere measurements in human cancer and aging using long-read nanopore sequencing
Time: Monday, April 8, 1:30 PM - 5:00 pm
Location: Section 53, LB185 / 1
Presenter: Steven Artandi, Stanford Cancer Institute
Sunday, April 7th
Translocation detection in cancer using low-pass pore-c sequencing
Time: 1:30 pm - 5:00 pm
Location: Section 17, 405/5
Presenter: Sergey Aganezov, Oxford Nanopore Technologies
Monday, April 8th
Telomere dynamics in aging and cancer by nanopore long-read sequencing
Time: 9:00 am - 12:30 pm
Location: Section 13, 1639 / 9
Presenter: Tobias Schmidt, Salk Institute For Biological Studies
Methylation based phylogeny and timing in cancer
Time: 9:00 am - 12:30 pm
Location: Section 37, 2333 / 11
Presenter: Ignaty Leshchiner, Boston University
Benchmarking long- and short-read somatic structural variation callers using a multi-technology panel of six tumor/normal cell lines
Time: 9:00 am - 12:30 pm
Location: Section 37, 2338 / 16
Presenter: Asher Bryant, Center for Cancer Research, National Cancer Institute
Solving the cancer mutation conundrum: A single cell, massively parallel approach for cancer mutation discovery, genome modelling and functional characterization
Time: 1:30 pm - 5:00 pm
Location: Section 14, 2928 / 3
Presenter: Hanlee P. Ji, Stanford University
Nanopore adaptive sampling detects nucleotide variants and improves large scale rearrangement characterization for diagnosis of cancer predisposition
Time: 1:30 pm - 5:00 pm
Location: Section 14, 2936 / 11
Presenter: Romain Boidot, Ctr. Georges-François Leclerc
Accurate detection of human papillomavirus breakpoints in cervical cancers using a novel library preparation strategy for nanopore sequencing technology
Time: 1:30 pm - 5:00 pm
Location: Section 14, 2937 / 12
Presenter: Amrita Parida, Kasturba Medical College
Tuesday, April 9th
A nanopore sequencing approach characterizes cell-free DNA methylation-fragmentomics profiles indicative of breast cancer in a large cohort
Time: 9:00 am - 12:30 pm
Location: Section 36, 4920 / 16
Presenter: Xiangqi Bai, Stanford University School of Medicine
Detecting chromosomal copy number variations and point mutations in Glioma using a single assay; sparing tissue while significantly reducing testing time and cost
Time: 9:00 am - 12:30 pm
Location: Section 41, 5049 / 3
Presenter: Mashiat Mimosa, University of Toronto
Haplotype-resolved analysis of cancer genomes and epigenomes using Oxford Nanopore sequencing
Time: 1:30 pm - 5:00 pm
Location: Section 36, 6218 / 21
Presenter: Philipp Rescheneder, Oxford Nanopore Technologies
Native nanopore sequencing of multiple tumor sites reveals genetic and epigenetic intra-tumor heterogeneity in canine osteosarcoma
Time: 1:30 pm - 5:00 pm
Location: Section 16, 5665 / 11
Presenter: Sergey Aganezov, Oxford Nanopore Technologies
Wednesday, April 10th
LongFuse: Detecting gene fusion transcripts from high throughput long-read single cell RNA sequencing data
Time: 9:00 am - 12:30 pm
Location: Section 35, 7418 / 13
Presenter: Cheng-Kai Shiau, Northwestern Univ. Feinberg School of Medicine
Identifying cell free DNA methylation signatures in cerebrospinal fluids for the early detection of brain metastasis in non-small cell lung cancer
Time: 9:00 am - 12:30 pm
Location: Section 15, 7019 / 19
Presenter: Tianqi Chen, Stanford University School of Medicine