RNA and cDNA sequencing
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Characterise whole transcriptomes
Oxford Nanopore technology uniquely delivers high outputs of any-length reads that span full-length RNA transcripts, facilitating their accurate, unambiguous analysis and resulting in complete transcriptome characterisation at the isoform level.
Nanopore RNA and cDNA sequencing generates novel insights into differential isoform expression and allele-specific expression, even at single-cell resolution — in one go. Furthermore, with direct RNA sequencing that does not require reverse transcription or amplification, it is possible to detect base modifications (such as methylation) in native RNA transcripts. The scalability of Oxford Nanopore sequencing devices means that researchers do not need to batch a high number of samples, reducing waiting times and generating faster results.
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The value of full-length transcripts without bias
Discover how nanopore sequencing enables unambiguous, full-length, isoform-level gene expression analysis, including identification, characterisation, and quantification. See how researchers use direct native RNA sequencing to simultaneously detect base modifications, such as methylation, in a single experiment.
Detecting isoforms and RNA modifications with nanopore sequencing
In this best-practice, end-to-end workflow, discover how to characterise full-length splice isoforms and RNA modifications with direct RNA nanopore sequencing.
High-definition transcriptomics
Recommended device for RNA and cDNA sequencing
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PromethION 2 Solo and 2 Integrated
Offering the flexibility of two independent, high-output PromethION Flow Cells, the compact PromethION 2 devices bring the benefits of high-coverage, real-time nanopore sequencing to every lab. Ideal for low-cost access to highly accurate whole transcriptomes.
