Bioinformatics

This guide introduces cDNA and direct RNA Oxford Nanopore sequencing, for ultra-rich transcriptomic data without compromise.

A guide to get started with sequencing microbial samples with Oxford Nanopore.

This guide provides an introduction to performing targeted nanopore sequencing.

This guide introduces how to sequence human genomes with Oxford Nanopore, from the construction of new, highly complete reference assemblies to the comprehensive identification of variants.

This guide provides an introduction to the direct sequencing of DNA methylation in human genomes.

This end-to-end workflow introduces how to enrich a comprehensive panel of PGx targets with real-time targeted Oxford Nanopore sequencing.

In this flyer, find out how Oxford Nanopore provides gold-standard methylation sequencing and comprehensive variant calling in a single run — without chemical conversion.

This end-to-end workflow provides a scalable method to identify previously hidden and potentially pathogenic variants.

In this brochure, discover Oxford Nanopore sequencing techniques that can reveal multidimensional insights for your microbial research applications.

This end-to-end workflow overview provides a simple solution for detecting a wide range of tumour-specific variation in a single sequencing assay.

In this flyer, find out how Oxford Nanopore provides gold-standard methylation sequencing and comprehensive variant calling in a single run — without chemical conversion.

In this brochure, discover Oxford Nanopore sequencing techniques that can reveal multidimensional insights for your microbial research applications.

Discover how the Oxford Nanopore and Twist Bioscience pharmacogenomic research workflow delivers PGx sequencing without compromise.

Discover how the Oxford Nanopore rapid whole-genome sequencing workflow is delivering fast, actionable results in 24 hours from sample collection.

Discover EPI2ME and how it provides data analysis for all levels of expertise

Unlock previously hidden variation with nanopore sequencing and characterise cancer at unprecedented resolution.

In this case study, researchers show that near-complete bacterial genomes can be assembled using nanopore sequencing alone.

Monitoring the genomic characteristics of pathogens circulating in a population can reveal important insights into the epidemiological dynamics of an outbreak. Unfortunately, sequencing every confirmed positive sample in a densely populated area is both challenging and expensive. Since viruses are s

BiographyAnna completed her Bachelor’s degree in Biology and specialised in Applied Bioinformatics during her Master’s studies at the Johannes Gutenberg University in Mainz. In 2019, Anna started her PhD at the Leibniz Institute for Resilience.AbstractRNA modification

Methylation has been implicated in the pathogenic mechanisms of many genetic diseases, such as Prader-Willi syndrome1 and fragile X syndrome (FXS)2. However, traditional sequencing methods require the use of amplification, which erases all epigenetic modifications. This means that the presence of me

This workflow extracts cell barcodes and UMIs from 10x-generated single cell libraries. It was initially created as a Nextflow port of Sockeye.

This repository contains a nextflow workflow for analysing variation in human genomic data.

This repository contains a nextflow workflow template that can be used as the basis for creating new workflows.

Transcriptome analysis of cDNA and direct RNA sequencing data.

wf-tb-amr is a workflow for determining the antibiotic resistance of Mycobacterium tuberculosis targeted sequencing samples.

Discover how strengthening local sequencing and bioinformatics capacity can support sustainable pathogen surveillance and informed public health responses across the Pacific.

Dr Pamela Gan is the Bioinformatics Team Lead at NalaGenetics, whose current primary research focus is developing bioinformatic pipelines and applications for diagnostics and personalized medicine. She holds a PhD from the Australian National University and has prior experience

Authors: Quentin RV. Ferry, Maurice Frank, Julia Jehn, Matthias Schaks, Bruno R. Steinkraus, Timothy Rajakumar

In this webinar, Dr Polona Le Quesne Stabej and Dr Zoe Ward from the University of Auckland discuss their research into DMPK repeat expansions and their role in inherited cardiac disease. Learn how sequencing on the PromethION 2 Integrated enabled the detection of a pathogenic repeat expansion.

Event abstract Oxford Nanopore basecallers use machine learning to achieve accurate and fast basecalling, provided by models that are the most suitable for the widest range of applications. However, training your own bespoke basecaller for your tailored experiment may provide application-specific