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Dorado basecall server

High-performance commandline basecaller in a client-server configuration as used in MinKNOW. Documentation is included in the package README.md.

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Version: 7.8.3

Release date: 4/16/2025

Approved use: For research use only

  • Functionality from Dorado v0.9.2
  • Model changes: updated to v5.1 RNA004 models with new m5C and inosine_m6A modifications for SUP
  • Basecall configuration changes: migrating from legacy config files
  • Automated GPU detection
  • Poly(A) tail estimation improvements
  • Adapter and primer trimming now uses sequencing kit information to decide what to trim
  • Short read filtering: reads shorter than 5nt will no longer be emitted to the fastq or BAM output files
  • Other output updates, minor changes and bug fixes
Release notesRelease history

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