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Dorado

High-performance, easy-to-use commandline basecaller for Nanopore data. Developer release for evaluation of new features. For information about the Dorado project, see https://github.com/nanoporetech/dorado.

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Dorado documentation
For more detailed advice, documentation and installation guides for Dorado

Version: 1.1.0

Release date: 7/31/2025

Approved use: For research use only

  • Basecalling speed improvements: Faster HAC basecalling models on a range of NVIDIA GPUs and faster Transformer-based SUP basecalling models running on NVIDIA Hopper GPUs
  • Output and tag updates for consistency with Oxford Nanopore Output Specifications
  • Support for primer detection and trimming for 10x Genomics libraries using --primer-sequences with Dorado basecaller and trim
  • Other feature improvements and simplifications
  • Bug fixes