Unified metagenomic method for rapid detection of microorganisms in clinical samples
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- Published on: July 7 2024
- Source: Communications Medicine
Identification of respiratory pathogens with existing metagenomic methods requires multiple assays over several days, and often provides an incomplete picture. Here the authors showcase a method using nanopore sequencing to rapidly isolate and sequence RNA and DNA-containing pathogens simultaneously, generating highly accurate results compared to routine techniques. They also demonstrated that the workflow can be performed completely onsite, with preliminary results available in 30 minutes.
