Transcriptome profiling of Korean colon cancer by cDNA PCR Nanopore sequencing

  • We have sequenced 20 pairs of Korean colon cancer patients using cDNA PCR Nanopore technology to identify colon cancer specific novel biomarkers that can be used for clinical usage.
  • We attempted to identify novel isoform, non-coding RNAs and fusion genes. Some candidates that were found were shown to have potential to be new colon cancer diagnostic biomarkers.
  • By using more precise and accurate data to detect such biomarkers, we want not only to be able to use them for clinical usage, but also to further propose a new molecular mechanism to better understand colon cancer tumorigenesis using Nanopore data.

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