Oxford Nanopore sequencing provides superior metagenome-assembled genome recovery and strain-level resolution from a complex microbiome

Overview

Metagenomics provides an essential tool for uncovering the taxonomic and genetic composition of microbial communities, offering insights into their biology, ecology, and evolution. Breakthroughs in long-read sequencing accuracy, as well as community tools capable of leveraging this data, are revolutionising the field.

This application note highlights how Oxford Nanopore sequencing serves as a standalone, efficient platform for high-resolution metagenomic analysis, providing unparalleled throughput and insights into complex microbial communities such as the human gut microbiome.

In this application note, you will:

• Learn the importance of generating highly complete and contiguous metagenome-assembled genomes (MAGs) from a complex microbiome
• Discover the methods and analysis tools used to generate high-quality data
• View our benchmarking data that shows the Oxford Nanopore platform provides superior performance for metagenomic analysis relative to other sequencing platforms