Ninetails: a comprehensive tool for investigation of non-adenosine residues within poly(A) tails from direct RNA sequencing data
- Published on: May 19 2023
Oxford Nanopore direct RNA sequencing (DRS) facilitated by the Ninetails package is the only method for the analysis of the composition of poly(A) tails, unaffected by reverse transcription and/or PCR amplification
Ninetails leverages a neural network trained for the detection of non-A residues within the poly(A) tails in DRS data
Ninetails can be used for visual inspection of DRS read signals
