Nanopore sequencing of native adeno-associated virus genomes to aid in gene therapy vector quality control
- Published on: May 15 2023
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Sequencing of full-length native AAV genomes on Nanopore devices allows identification of truncation hotspots, plasmid and cell line contamination, and mutation hotspots
Download the poster to find out more about:
- How adeno-associated virus (AAV) is used for gene therapy
- How the EPI2METM Labs’ wf-clone-validation' workflow can be used to validate AAV plasmid constructs
- How full-length native AAV genomes and vector contamination are identified with nanopore sequencing
- How to generate consensus sequences and identify truncation hotspots
