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LAST

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Martin Frith, Computational Biology Research Center in Tokyo

Release Date: 18-Sep-2015

LAST finds similar regions between sequences, and aligns them. It is designed for comparing large datasets to each other (e.g. vertebrate genomes and/or large numbers of DNA reads). It can:

  • Indicate the (un)ambiguity of each column in an alignment
  • Use sequence quality data in a rigorous fashion
  • Align DNA to proteins with frameshifts
  • Compare PSSMs to sequences
  • Calculate the likelihood of chance similarities between random sequences
  • Do split and spliced alignment
Authors: Martin Firth
Read the full text
  • Published on: April 20 2015
  • Source: LAST: Genome-Scale Sequence Comparison

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