Identification of novel genomic structures and regulation patterns at HPV integration events in cervical cancer
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- Identification of novel genomic structures and regulation patterns at HPV integration events in cervical cancer
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Human papillomavirus (HPV) infection is necessary in the development of cervical cancer. Often, part of the transformation into cancer is the integration of the HPV genome into the host genome1. The integrated form of HPV changes the regulation of HPV genes, and transforms the genome and epigenome at the regions harbouring HPV2.