Continental-scale genomic surveillance of *Plasmodium falciparum* malaria with rapid nanopore sequencing
)
- Published on: July 23 2025
- Source: bioRxiv
To support real-time malaria surveillance in sub-Saharan Africa, Mwenda et al. investigated the use of Oxford Nanopore sequencing to analyse over 1,000 dried blood spots. This low-cost, portable method accurately detected drug-resistance mutations and gene deletions associated with diagnostic test evasion, even at low parasite levels — offering an accessible, rapid solution for local labs to monitor outbreaks and guide public health responses.
'Our [Oxford Nanopore sequencing] approach will accelerate genomic surveillance of P. falciparum malaria across sub-Saharan Africa at a time of urgent need'
Mwenda et al. 2025
Sample type: dried blood spots
Kit: Rapid Barcoding Kit
