Accelerating cancer research through comprehensive genomic analysis
The rapid advancement of sequencing technologies over the last two decades has delivered unprecedented insights into the structure and functions of the human genome. Replacing more cumbersome, low-resolution techniques for human genome analysis, such as karyotyping and microarrays, researchers can now use high-throughput sequencing technologies for routine analysis of human genome samples to uncover causative variations for a range of diseases and disorders — at nucleotide resolution.
Download white paper:
Overview
In this white paper, you will learn how cancer researchers are using nanopore sequencing to overcome the key challenges associated with short-read sequencing technologies to deliver:
- More compete and contiguous cancer genome assemblies
- Accurate resolution of structural variants and repeat regions
- Rapid identification of fusion genes and full-length transcript isoforms
- Detection of low-abundance cell-free DNA (cfDNA) and circulating tumour DNA (ctDNA)
- Streamlined sequencing of targeted regions and panels
- Epigenetic base modification detection as standard — no additional sample prep or sequencing runs required
Read customer case studies describing the detection of a wide variety of genomic variants across a wide range of cancers, including cervical cancer, colorectal cancer, acute myeloid leukaemia, and tumeroids.
