Nanopore sequencing in neurology research: see the whole picture. A Dementia Research Institute and Oxford Nanopore Technologies Webinar
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This exciting neurology-focused research webinar features updates from Oxford Nanopore Technologies, and presentations from researchers who have applied nanopore sequencing for genomic, epigenomic and transcriptomic analysis. This webinar will highlight how you can utilise Oxford Nanopore platforms within the DRI network to enable omics analysis.
Highlights
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Emmanuelle Vire: Nanopore sequencing to detect prion protein gene mutations
Prion diseases are fatal conditions. In her talk, Emmanuelle Vire discussed how her team used MinION to sequence the full length of PRNP to assess the contribution of variants & SVs within non-coding regions, inaccessible to current short-read methods.
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Nicola Hall: Brain-enriched transcript isoforms as potential tissue-selective treatment targets
Hear how Nicola Hall used long nanopore reads and a custom pipeline to characterise the full-length mRNA isoforms of CACNA1C, in adult human brain, heart and aorta, with the aim to identify brain-enriched isoforms & potentially new psychiatric drug targets.
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Wouter De Coster: Tandem repeat variability in frontotemporal dementia: a population scale assessment
Wouter De Coster discussed his population-scale investigation of tandem repeat variability in frontotemporal dementia and how nanopore sequencing dramatically improves the resolution for repeat analysis.
