Resource Centre
Unprecedented access to haplotype-resolved biology enabled by ultra-long reads and Pore-C
- Chromatin conformation
- Phasing
- SNVs
- Long-read
- PromethION
- Methylation
Understanding the binding of multiple transcription factors by base-pair-resolution chromatin accessibility
- Chromatin conformation
- Clinical research
- Bioinformatics
- Human genomics
- MinION
- Epigenetics
Telomere-to-telomere nanopore-based genome assembly reveals genomic and epigenetic features of karyotype radiation
- Chromatin conformation
- Animal
- Bioinformatics
- Epigenetics
- Structural variation
- Long-read
Single-molecule long-read sequencing reveals chromatin basis of gene expression
- Chromatin conformation
- Gene expression
- Human genomics
Single-molecule long-read sequencing reveals the chromatin basis of gene expression
- Chromatin conformation
- gDNA
- Epigenetics
- Methylation
- Transcriptome
- Microbiology
Sequencing of methylase-accessible regions in integral circular extrachromosomal DNA reveals differences in chromatin structure
- Chromatin conformation
- Long-read
- Methylation
- Protocols
- DNA
- Epigenetics
Positional mapping of active versus silenced rRNA gene clusters within A. thaliana nucleolus organizer regions
- Chromatin conformation
- Bioinformatics
- Plant
- GridION
- Assembly
- Epigenetics
Pore-C simultaneously captures genome-wide multi-way chromatin interaction and associated DNA methylation status in Arabidopsis
- Chromatin conformation
- Methylation
- Epigenetics
- DNA
- Plant
Pore-C: a method for genome-wide, multi-contact chromosome conformation capture
- Chromatin conformation
- London Calling
- Whole genome
Persistent chromatin states, pervasive transcription, and shared cis-regulatory sequences have shaped the C. elegans genome
- Chromatin conformation
- Transcriptome
- Gene expression
- RNA
- cDNA
- MinION
One fly-one genome: chromosome-scale genome assembly of a single outbred Drosophila melanogaster
- Chromatin conformation
- Assembly
- Sample prep
- gDNA
- DNA
- Whole genome
A new Spirodela polyrhiza genome and proteome reveal a conserved chromosomal structure with high abundances of proteins favoring energy production
- Chromatin conformation
- Plant
- Whole genome
- Assembly
- gDNA
- DNA
NCM 2022: Use of Pore-C to explore the 3D organization of animal symbiont chromosomes
- Chromatin conformation
- Bioinformatics
- Environment
- Epigenetics
- Metagenomics
- Microbiology
NCM 2021: The genetic and epigenetic landscape of the Arabidopsis centromeres
- Chromatin conformation
- Assembly
- Epigenetics
- Plant
- MinION
- Flongle
NCM 2021: Real-time cancer classification with nanopore sequencing
- Chromatin conformation
- Bioinformatics
- Cancer research
- Epigenetics
- Clinical research
- Human genomics
NCM 2023 Singapore: Direct detection of DNA modifications in human cancer genomes
- Chromatin conformation
- Bioinformatics
- Cancer research
- Epigenetics
- Gene expression
- Human genomics
Nanopore sequencing reveals conservation of chromosome end-specific telomere lengths
- Chromatin conformation
- Cancer research
- Human genomics
- MinION Mk1B
- London Calling
Nanopore sequencing of DNA concatemers reveals higher-order features of chromatin structure
- Chromatin conformation
- Assembly
- Human genomics
- Whole genome
- DNA
- gDNA
Nanopore sequencing and Hi-C scaffolding provide insight into the evolutionary dynamics of transposable elements and piRNA production in wild strains of Drosophila melanogaster
- Chromatin conformation
- Whole genome
- Assembly
- Long-read
- MinION
- Animal
Multi-contact chromosome conformation capture using nanopore sequencing in nematodes
- Chromatin conformation
- London Calling
- Epigenetics