SNVs and phasing

This guide provides an introduction to performing targeted nanopore sequencing.

This guide introduces how to sequence human genomes with Oxford Nanopore, from the construction of new, highly complete reference assemblies to the comprehensive identification of variants.

This guide introduces the single-cell RNA nanopore sequencing workflow, for ultra-rich data without compromise.

This end-to-end workflow introduces how to enrich a comprehensive panel of PGx targets with real-time targeted Oxford Nanopore sequencing.

This end-to-end workflow provides a scalable method to identify previously hidden and potentially pathogenic variants.

Discover the Hereditary Cancer Panel workflow and streamline your precision oncology research.

This end-to-end workflow overview provides a simple solution for detecting a wide range of tumour-specific variation in a single sequencing assay.

This end-to-end workflow introduces how to perform rapid whole-genome human variant and methylation calling from a blood research sample using high-output DNA sequencing on PromethION 24.

In this flyer, discover how to utilise the Oxford Nanopore Hereditary Cancer Panel to investigate 258 key genes associated with hereditary cancer risk.

In this application note, we present the design and performance of the Oxford Nanopore Hereditary Cancer Panel targeting 258 key genes implicated in cancer predisposition.

In this flyer, find out how Oxford Nanopore provides gold-standard methylation sequencing and comprehensive variant calling in a single run — without chemical conversion.

Discover how the Oxford Nanopore and Twist Bioscience pharmacogenomic research workflow delivers PGx sequencing without compromise.

Discover how the Oxford Nanopore rapid whole-genome sequencing workflow is delivering fast, actionable results in 24 hours from sample collection.

Homologous recombination deficiency (HRD) affects breast, ovarian, pancreas and prostate cancers. Patients with HRD tumours can respond to poly ADP-ribose polymerase (PARP) inhibitors and platinum-based therapies. HRD results in a variety of single base, insertion and deletion, and large structural

Timely and comprehensive molecular classification is essential for therapeutic decision-making in pediatric oncology, yet current diagnostic workflows rely on multi-step, time- and resource-intensive testing. We present a standardized Oxford Nanopore Technologies whole-genome sequencing approach usi

What if targeted sequencing took place during sequencing itself, without the need for special library prep, PCR, or probes? In this demo, discover Adaptive Sampling: a unique, real-time targeted enrichment/depletion method that achieves just that.

Whether you’re sequencing DNA, RNA, or cDNA, a single sample or many in multiplex, there’s an Oxford Nanopore library prep kit for you. In this masterclass, discover how to choose the right one for your workflow.

In this case study, researchers show that near-complete bacterial genomes can be assembled using nanopore sequencing alone.

This is a single-cell transcriptomics method.

This is a 10X Genomics Visium Spatial transcriptomics method.

This protocol describes how to carry out sequencing of cDNA from single cells using the PCR-cDNA Sequencing Kit (SQK-PCS111). You will need to have reverse-transcribed single cell mRNA into cDNA using the 10X Genomics Next GEM Single Cell 3' Kit (V3.1).

This repository contains a nextflow workflow for analysing variation in human genomic data.

This workflow calls variants from the alignment files of a paired tumor/normal sample.

The wf-artic workflow implements a slightly modified ARTIC FieldBioinformatics workflow for the purpose of preparing consensus sequences from SARS-CoV-2 genomes that have been DNA sequenced using a pooled tiling amplicon strategy.

Joy Goffena is a Research Scientist in Dr Danny Miller’s lab at the University of Washington. She specializes in applying Oxford Nanopore Technologies sequencing to advance genetic research and clinical diagnostics. Her work focuses on identifying causal genetic variants...

Highlighted publications showing how researchers are using Oxford Nanopore sequencing for pharmacogenomics (PGx) research.

Event overview Knowledge Exchanges provide the perfect opportunity to hear some of the very latest developments in nanopore sequencing from members of the Oxford Nanopore team. In this Knowledge Exchange, Philipp Rescheneder shares how the long-read capabilities of nanopore sequencing can be u

Authors: Rhys T. White, Michelle Balm, Megan Burton, Samantha Hutton, Jamaal Jeram, Matthew Kelly, Donia Macartney-Coxson, Tanya Sinha, Henrietta Sushames, David J. Winter, Maxim G. Bloomfield

Discover how nanopore sequencing with Adaptive Sampling can target cancer-associated genes from blood-derived and bone marrow-derived DNA.