Chromatin conformation
Featured resources
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Leveraging base modification information with Modkit | LC26
Nanopore sequencing reads from native DNA and RNA are inherently multiomic. However, using this data with confidence can be daunting. I will show how improvements in machine learning models have made it easier than ever to acquire this data. Then we will touch on best practices for a variety of exam
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Epitranscriptomic regulation of the developing human pancreas | LC26
RNA modifications are crucial regulators of gene expression in human development. They have an established role in regulating pancreatic β-cell development and function, with dysregulation resulting in diabetes. Numerous limitations have restricted the study of these modifications directly in pancre
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The long and short of it
Kicking off the second plenary of NCM 2019 was Sissel Juul, Director of Genomic Application at Oxford Nanopore. Sissel began by introducing the applications team: in Oxford, United Kingdom, the group focus on sample technology, whilst the Genomic Applications team is split across Oxford, New York an
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Update from Oxford Nanopore Technologies
Clive Brown is CTO of Oxford Nanopore, where he leads the innovation of breakthrough technologies and product development, that are designed to enable the analysis of anything, by anyone, anywhere.
Clive has held a variety of roles in Genomics and Genetic R&D, he also played a key role...
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Expanding reference genomes with T2T assembly to reflect global diversity
Discover how researchers are utilising Oxford Nanopore data to generate telomere-to-telomere (T2T) genomes, addressing the critical gaps in reference genomes.
Protocols
Chromatin accessibility sequencing from cell samples using SQK-LSK114
This protocol describes an end-to-end process to prepare and sequence gDNA for chromatin accessibility from cell samples, and to analyse the data using the information outlined in our chromatin accessibility data and tool release on the EPI2ME page.
Latest research
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A hybrid genome assembly of the endangered aye-aye (Daubentonia madagascariensis)
Publication: A hybrid genome assembly of the endangered aye-aye (Daubentonia madagascariensis)
A ONECUT1 regulatory, non-coding region in pancreatic development and diabetes
Publication: A ONECUT1 regulatory, non-coding region in pancreatic development and diabetes
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Complete sequencing of ape genomes
Publication: Complete sequencing of ape genomes
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Complex genetic variation in nearly complete human genomes
Publication: Complex genetic variation in nearly complete human genomes
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DeepNanoHi-C: deep learning enables accurate single-cell nanopore long-read data analysis and 3D genome interpretation
Publication: DeepNanoHi-C: deep learning enables accurate single-cell nanopore long-read data analysis and 3D genome interpretation
