Discover nanopore sequencing

What can it do? How does it work? Our platform performance and accuracy

Explore products

Prepare Sequence Analyse
Store Resources Support About
MinION GridION PromethION Flongle
PromethION 24 & 48

Flexible, large-scale, direct DNA and RNA sequencing

Terabases of data

1 - 48 flow cells

Flexible, on-demand sequencing

High-performance compute

Analyse data in real time with 4 NVIDIA A-Series GPUs

Up to 13.3 Tb data*

* (Theoretical max output when system is run for 72 hours at 400 bases / second. Outputs may vary according to library type, run conditions, etc.)


Flexible DNA/RNA high-throughput nanopore sequencers Offering the flexibility of 24 independently controllable, high-output flow cells and leveraging state-of-the-art algorithms and GPU technology, PromethION 24 (P24) provides single or multiple users with on-demand access to terabases of sequencing data. PromethION 48 (P48), our most powerful sequencing device, delivers twice the capacity and output of P24 — ideal for large- and production-scale sequencing projects.

Book a sales call
PromethION 24 and PromethION 48


Two PromethION models are available for high-throughput sequencing projects: the PromethION 24 (P24) and PromethION 48 (P48), respectively operating up to 24 and 48 flow cells at once. Both systems are deployed with the powerful PromethION A-Series tower, utilising 4 NVIDIA A-Series GPUs for real-time data handling.

Read length

Nanopores read the length of DNA or RNA presented to them — from short to ultra-long (longest >4 Mb)


Compact benchtop device with compute module

Sequencing module:

  • Size: W 590 mm, H 190 mm, D 430 mm
  • Weight: 28 kg

Compute module:

  • Size: W 178 mm, H 440 mm, D 470 mm
  • Weight: 25 kg

Up to 277 Gb per flow cell*

Total device output as much as:

  • Up to 6.6 Tb PromethION 24*
  • Up to 13.3 Tb PromethION 48*

* Theoretical max output when system is run for 72 hours at 400 bases / second. Outputs may vary according to library type, run conditions, etc.

Suitable applications

  • Larger genomes or projects
  • Population-scale sequencing
  • Highly multiplexed small genomes or targeted regions
  • Whole transcriptomes (direct RNA or cDNA)

On demand

Sequence what you need, when you need it

  • Run flow cells individually or together — no more sample batching
  • Each flow cell has approximately six times the sequencing capacity of a MinION Flow Cell
  • Run multiple DNA or RNA experiments at once
  • Barcode for even more samples
  • Suitable for high-throughput and service labs


  • No capital cost
  • Small footprint — suitable for any lab
  • Easy installation with comprehensive support

High-performance compute

Sequencing and analysis in one powerful device

  • Latest generation CPU
  • 4 NVIDIA A-Series GPUs
  • 60 TB SSD data storage
  • 512 GB RAM
  • Preloaded with Ubuntu OS and MinKNOW
Nanopore Service Certified

Service provider certification is available for PromethION

Find out more

Capturing global genomic diversity in the human pangenome with long nanopore reads

The team used the PromethION sequencing device from Oxford Nanopore Technologies to generate ultra-long reads from each of the 47 samples. For the 29 samples sequenced entirely by the consortium, the average read length was 28.4 kb; for 18 additional samples with prior sequencing data from other sources, the nanopore read length N50 value was approximately 44 kb.

Read more

For large-cohort dementia research, nanopore sequencing offers scalability and accessibility

The use of long nanopore reads to support large-scale studies of dementia, the successful application of this approach in characterizing complex genomic regions associated with Alzheimer’s disease and other forms of dementia, enabling the identification of structural variants and facilitating comprehensive analysis of DNA methylation patterns across different brain regions.

Read more

Understanding the drivers of oncogenesis

In his talk, The potential of nanopore sequencing for personalised oncogenomics, Kieran O’Neill introduced the Personalized OncoGenomics (POG) Program research trial, which has been running for over 12 years, and has involved the sequencing of over 1,000 genomes and transcriptomes from clinical research samples from participants with advanced cancer...

Read more

Product documentation

PromethION P24/P48 device specs

PromethION 24 Technical Specification

158 KB PDF

PromethION IT Requirements

This checklist represents the minimal requirements for installing the PromethION in your institution.

192 KB PDF

Safety and regulatory information

110.7 KB PDF

PromethION Quick Start Guide

335 KB PDF


Get in touch

Talk to us

If you have any questions about our products or services, chat directly with a member of our sales team.

Talk to us

Book a sales call

To book a call with one of our sales team, please click below.

Book a call