PromethION 24 & 48 group
Flexible, large-scale, direct DNA and RNA sequencing

Terabases of data

1 - 48 flow cells

Flexible, on-demand sequencing

High-performance compute

Analyse data in real time with 4 NVIDIA A-Series GPUs

Up to 13.3 Tb data*

* (Theoretical max output when system is run for 72 hours at 400 bases / second. Outputs may vary according to library type, run conditions, etc.)


Flexible DNA/RNA high-throughput nanopore sequencers offering the flexibility of 24 independently controllable, high-output flow cells and leveraging state-of-the-art algorithms and GPU technology, PromethION 24 (P24) provides single or multiple users with on-demand access to terabases of sequencing data. PromethION 48 (P48), our most powerful sequencing device, delivers twice the capacity and output of P24 — ideal for large- and production-scale sequencing projects.

PromethION 24 & 48 on a white background


Two PromethION models are available for high-throughput sequencing projects: the PromethION 24 (P24) and PromethION 48 (P48), respectively operating up to 24 and 48 flow cells at once. Both systems are deployed with the powerful PromethION A-Series tower, utilising 4 NVIDIA A-Series GPUs for real-time data handling.

PromethION angled view
Read length

Nanopores read the length of DNA or RNA presented to them — from short to ultra-long (longest >4 Mb)


Compact benchtop device with compute module

Sequencing module:

  • Size: W 590 mm, H 190 mm, D 430 mm

  • Weight: 28 kg Compute module:

  • Size: W 178 mm, H 440 mm, D 470 mm

  • Weight: 25 kg

Up to 277 Gb per flow cell*

Total device output as much as:

  • Up to 6.6 Tb PromethION 24*
  • Up to 13.3 Tb PromethION 48*

* Theoretical max output when system is run for 72 hours at 400 bases / second. Outputs may vary according to library type, run conditions, etc.

Suitable applications
  • Larger genomes or projects
  • Population-scale sequencing
  • Highly multiplexed small genomes or targeted regions
  • Whole transcriptomes (direct RNA or cDNA)
On demand

Sequence what you need, when you need it

  • Run flow cells individually or together — no more sample batching
  • Each flow cell has approximately six times the sequencing capacity of a MinION Flow Cell
  • Run multiple DNA or RNA experiments at once
  • Barcode for even more samples
  • Suitable for high-throughput and service labs
  • No capital cost
  • Small footprint — suitable for any lab
  • Easy installation with comprehensive support
High-performance compute

Sequencing and analysis in one powerful device

  • Latest generation CPU
  • 4 NVIDIA A-Series GPUs
  • 60 TB SSD data storage
  • 512 GB RAM
  • Preloaded with Ubuntu OS and MinKNOW
PromethION 2 black background
ONT Service Certified logo

Service provider certification is available for PromethION


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