Library preparation automation

Straightforward library prep automation allows users to generate premium quality data around the clock with minutes of hands-on time.

Automated prep for answers with impact

The range of devices available from Oxford Nanopore enable sequencing at every scale — from the single-use Flongle Flow Cell generating 1-2 Gbases of data, right through to the PromethION 48 with terabase-scale outputs. Automation of library preparation can help throughout this range. It improves the overall consistency of results, supporting robust and standardised workflows, which enables increased sample throughput for medium- and large-scale projects, such as large cohort studies. Our streamlined library preparation kits are easy to automate, and protocols are available for a range of liquid handlers.

Automation illustration diagram

Methods and their development

Oxford Nanopore Technologies has partnered with multiple automation vendors to support our users' needs. These partnerships enable support at every level of throughput, from standalone systems within research groups to high-throughput, integrated systems for population-scale sequencing projects. Alongside in-house method development, we work with vendors and users to design, develop, and validate methods tailored to your workflow. Through an open platform approach, we aim to support any user wishing to automate library preparation for nanopore sequencing, ensuring the delivery of real-time, information-rich data in a reliable and automated manner.

Hamilton Tecan Beckman Coulter Opentrons Agilent Eppendorf
NGS STAR STAR STARlet DreamPrep NGS Biomek i-7 OT-2 Bravo epMotion 5073t epMotion 5075t
Ligation Sequencing Kit XL V14
(LSK114-XL)
Qualified ONT Vendor script Qualified ONT Vendor script Vendor script
Native Barcoding Kit 96 V14
(NBD114.96)
ONT Development Vendor script Vendor script
Multiplex Ligation Sequencing Kit V14
(MLK-114)
ONT Development ONT Development
Multiplex Ligation Sequencing Kit (MLK111.96-XL) Qualified ONT
Midnight RBK
(RBK110.96 & EXP-MRT001)
Qualified ONT Vendor script Qualified ONT Qualified ONT Vendor script

Resources

Abstract DNA graphic

High-throughput DNA library preparation with DreamPrep® NGS and Ligation Sequencing Kit XL V14 for nanopore sequencing

High-throughput DNA library preparation with DreamPrep® NGS and Ligation Sequencing Kit XL V14 for nanopore sequencing

Seeking assistance? Get in touch

Whether you're considering lab automation, selecting the right platform, exploring new method development, or simply want more information, reach out to us. Our Automation Solutions Team is here to guide you through every phase of designing and implementing lab automation.

Get in touch

Streamlined and automated nanopore sequencing

Leveraging the advantages of our technology, centred around the flow cell and the compact size of our sequencers, you can automate your sequencing workflows. Our versatile automation solutions include portable and benchtop devices that are capable of sample extraction, library prep, sequencing, and even data analysis — all within a single device.

Learn more

TurBOT

Sample-to-answer benchtop device:
Extract, prepare, sequence, analyse

TraxION (coming soon)

Sample-to-sequence portable device:
Extract, prepare, sequence