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Oxford Nanopore Technologies

Matthew Jones

Matthew Jones
Job title
Institution
Stanford University, USA
Biography

Matthew Jones, PhD is a postdoctoral scholar at Stanford University, USA, advised by Howard Chang, MD, PhD. His work centres on developing computational and technological approaches to better understand evolution in biological systems, especially applied to cancer. Previously, Matthew earned his PhD from University of California, San Francisco, advised by Dr. Jonathan Weissman and Dr. Nir Yosef, where he developed algorithms for reconstructing tumor lineages from CRISPR-based lineage tracers. His current research focuses on better elucidating the role of extrachromosomal DNA (ecDNA) in tumor progression and drug resistance. Matthew is currently supported by an NCI K99/R00 Early-Career Postdoctoral Fellowship.

Recent publications

Zhu, K., et al. CoRAL accurately resolves extrachromosomal DNA genome structures with long-read sequencing. BioRxiv. 580594 (2024). DOI: https://doi.org/10.1101/2024.02.15.580594

King, L.H. Coordinated inheritance of extrachromosomal DNA species in human cancer cells. BioRxiv. 549597 (2023). DOI: https://doi.org/10.1101/2023.07.18.549597

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