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London Calling 2024 - Speakers

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Oxford Nanopore Technologies

Prof. Laurent Mesnard

Laurent Mesnard
Job title
Institution
Sorbonne University, France
Biography

Professor Laurent Mesnard is Head of the Intensive Care Nephrology Unit at Assistance Publique Hopitaux de Paris Tenon Hospital, Sorbonne University, Paris, and a national coordinator for the French National plan of sequencing (PFMG2025) for rare adult kidney diseases. He co-coordinates the National Thrombotic Microangiopathies network (CNR-MAT). Prof. Mesnard’s team, located in Paris, use short-read whole-exome/genome sequencing for the clinical diagnosis of adult chronic kidney disease. They also develop applications for long-read sequencing technologies to accelerate clinical diagnosis for rare kidney diseases at their ICU admission. Another project (Allogenomics) aims to develop new metrics to evaluate the risk of chronic kidney graft failure and better allocation strategies for kidney transplantation.

Recent publications

Doreille, A., Rafat, C., Rondeau, E., and Mesnard, L. How I treat thrombotic microangiopathy in the era of rapid genomics. Blood 141(2):147–155 (2023). DOI: https://doi.org/10.1182/blood.2022015583

Doreille, A. et al. Exome-first strategy in adult patients with CKD: a cohort study. Kidney Int Rep. 8(3):596–605 (2022). DOI: https://doi.org/10.1016/j.ekir.2022.12.007

Doreille, A. et al. Diagnostic utility of exome sequencing for kidney disease. N Engl J Med. 380:2079–2080 (2019). DOI: https://doi.org/10.1056/NEJMoa1806891

Talks at this conference

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