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London Calling 2024 - Speakers

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Oxford Nanopore Technologies

Dr. Luca Mazzarella

Luca Mazzarella
Job title
Institution
European Institute of Oncology, Italy
Biography

Dr. Luca Mazzerella is a physician scientist who specializes in medical oncology in Milan, Italy. He obtained his PhD in molecular biology at Imperial College London. Currently, Luca runs the laboratory of Translational Oncology at the European Institute of Oncology (IEO) in Milan, where he focuses on cancer genomics and bioinformatics across multiple cancers. As a clinician, he has worked for several years in phase-1 trials, and recently moved into gastrointestinal oncology.

Recent publications

Di Chiaro, P. et al. Mapping functional to morphological variation reveals the basis of regional extracellular matrix subversion and nerve invasion in pancreatic cancer. Cancer Cell 42(4):662–681 E10 (2024). DOI: https://doi.org/10.1016/j.ccell.2024.02.017

Magi, A. et al. High-resolution nanopore methylome-maps reveal random hyper-methylation at CpG-poor regions as driver of chemoresistance in leukemias. Comm Biol. A6(1):382 (2023). DOI: 10.1038/s42003- 023-04756-8. Erratum in: Commun Biol. 6(1):455 (2023).

Favalli, V. et al. Machine learning-based reclassification of germline variants of unknown significance: the RENOVO algorithm. Am J Hum Gen. 108(4):682–695 (2021). DOI: 10.1016/j.ajhg.2021.03.010

Talks at this conference

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