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Software release 1.2.0 for Dorado

Version: 1.2.0

Release date: 10/21/2025

Approved use: For research use only

  • Significant improvements to short read basecalling speed
  • Better CPU performance in situations where Dorado is not GPU-bound
  • Output and tag updates for consistency with Oxford Nanopore Output Specifications
  • Skip secondary/supplementary records from input aligned BAM in Dorado aligner
  • Allow per-barcode disabling of poly(A) estimation
  • Move table is now emitted to FASTQ if --emit-moves is set
  • Dorado basecaller will scale input data based on open_pore_level if present in POD5 files
  • Support Dorado basecaller model discovery from --models-directory if a full model name is specified
  • Enable automatic batch size selection in Dorado variant and polish
  • Update to Torch 2.7.1 and switch to using shared Torch libraries
  • Update POD5 library to 0.3.34
  • Other bug fixes and improvements

Last updated: 10/21/2025

Latest version: 1.2.0

Approved use: For research use only

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