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Software release 0.5.0 for Dorado

Version: 0.5.0

Release date: 12/5/2023

  • v4.3 basecalling models with speed and accuracy enhancements
  • Support for calling base modifications with duplex basecalling (hemi-methylation)
  • Primer and adapter trimming
  • Automatic model selection
  • Support for custom barcode arrangements and sequences
  • Add MN tag to ouput BAM to assist downstream tools in interpreting modified base tags
  • Improvements to speed and stability of basecalling on Apple silicon
  • Additional bug fixes and usability improvements

Last updated: 2/19/2026

Latest version: 1.4.0

Approved use: For research use only

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