Resource Centre
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Unprecedented access to haplotype-resolved biology enabled by ultra-long reads and Pore-C
- Chromatin conformation
- Phasing
- SNVs
- Long-read
- PromethION
- Methylation
May 15 2023
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Understanding the binding of multiple transcription factors by base-pair-resolution chromatin accessibility
- Chromatin conformation
- Clinical research
- Bioinformatics
- Human genomics
- MinION
- Epigenetics
September 17 2024
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Telomere-to-telomere nanopore-based genome assembly reveals genomic and epigenetic features of karyotype radiation
- Chromatin conformation
- Animal
- Bioinformatics
- Epigenetics
- Structural variation
- Long-read
May 19 2023
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Single-molecule long-read sequencing reveals chromatin basis of gene expression
- Chromatin conformation
- Gene expression
- Human genomics
December 10 2019
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Single-molecule long-read sequencing reveals the chromatin basis of gene expression
- Chromatin conformation
- gDNA
- Epigenetics
- Methylation
- Transcriptome
- Microbiology
June 14 2019
Sequencing of methylase-accessible regions in integral circular extrachromosomal DNA reveals differences in chromatin structure
- Chromatin conformation
- Long-read
- Methylation
- Protocols
- DNA
- Epigenetics
April 2 2021
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Positional mapping of active versus silenced rRNA gene clusters within A. thaliana nucleolus organizer regions
- Chromatin conformation
- Bioinformatics
- Plant
- GridION
- Assembly
- Epigenetics
September 17 2024
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Pore-C simultaneously captures genome-wide multi-way chromatin interaction and associated DNA methylation status in Arabidopsis
- Chromatin conformation
- Methylation
- Epigenetics
- DNA
- Plant
January 21 2022
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Pore-C: a method for genome-wide, multi-contact chromosome conformation capture
- Chromatin conformation
- London Calling
- Whole genome
May 29 2019
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Persistent chromatin states, pervasive transcription, and shared cis-regulatory sequences have shaped the C. elegans genome
- Chromatin conformation
- Transcriptome
- Gene expression
- RNA
- cDNA
- MinION
October 24 2019
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One fly-one genome: chromosome-scale genome assembly of a single outbred Drosophila melanogaster
- Chromatin conformation
- Assembly
- Sample prep
- gDNA
- DNA
- Whole genome
June 3 2020
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A new Spirodela polyrhiza genome and proteome reveal a conserved chromosomal structure with high abundances of proteins favoring energy production
- Chromatin conformation
- Plant
- Whole genome
- Assembly
- gDNA
- DNA
January 24 2020
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NCM 2022: Use of Pore-C to explore the 3D organization of animal symbiont chromosomes
- Chromatin conformation
- Bioinformatics
- Environment
- Epigenetics
- Metagenomics
- Microbiology
December 7 2022
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NCM 2021: The genetic and epigenetic landscape of the Arabidopsis centromeres
- Chromatin conformation
- Assembly
- Epigenetics
- Plant
- MinION
- Flongle
December 2 2021
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NCM 2021: Real-time cancer classification with nanopore sequencing
- Chromatin conformation
- Bioinformatics
- Cancer research
- Epigenetics
- Clinical research
- Human genomics
December 2 2021
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NCM 2023 Singapore: Direct detection of DNA modifications in human cancer genomes
- Chromatin conformation
- Bioinformatics
- Cancer research
- Epigenetics
- Gene expression
- Human genomics
September 27 2023
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Nanopore sequencing reveals conservation of chromosome end-specific telomere lengths
- Chromatin conformation
- Cancer research
- Human genomics
- MinION Mk1B
- London Calling
May 24 2024
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Nanopore sequencing of DNA concatemers reveals higher-order features of chromatin structure
- Chromatin conformation
- Assembly
- Human genomics
- Whole genome
- DNA
- gDNA
November 7 2019
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Nanopore sequencing and Hi-C scaffolding provide insight into the evolutionary dynamics of transposable elements and piRNA production in wild strains of Drosophila melanogaster
- Chromatin conformation
- Whole genome
- Assembly
- Long-read
- MinION
- Animal
November 22 2019
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Multi-contact chromosome conformation capture using nanopore sequencing in nematodes
- Chromatin conformation
- London Calling
- Epigenetics
May 24 2018