Resource Centre
2383 results
High-coverage nanopore sequencing of samples from the 1000 Genomes Project to build a comprehensive catalogue of human genetic variation
- Human genomics
- PromethION
- Methylation
- Structural variation
- Whole genome
- Variant calling
October 2 2024
Evaluation of a next generation sequencing assay for Hepatitis B antiviral drug resistance on the Oxford Nanopore system
- Infectious disease
- Amplicons
- GridION
- Guppy
October 2 2024
The rapid detection of a neonatal unit outbreak of a wild-type Klebsiella variicola using decentralised Oxford Nanopore sequencing
- Infectious disease
- Bacteria
- Whole genome
- MinION
- MinKNOW
October 1 2024
Giant extrachromosomal element “Inocle” potentially expands the adaptive capacity of the human oral microbiome
- Microbiology
- Plasmid
- Bacteria
- PromethION
October 1 2024
A rare case report of Prevotella lung abscess diagnosed using third-generation metagenomic sequencing
- Microbiology
- Clinical research
- MinION
September 26 2024
Long-read whole-genome sequencing-based concurrent haplotyping and aneuploidy profiling of single cells
- Bioinformatics
- Single cell
- Phasing
- Variant calling
- PromethION
September 25 2024
Implementing portable, real-time 16S rRNA sequencing in the healthcare sector enhances antimicrobial stewardship
- Microbiology
- Infectious disease
- rRNA
- Clinical research
September 25 2024
Complex genetic variation in nearly complete human genomes
- Human genomics
- Whole genome
- PromethION
September 25 2024
Development and extensive sequencing of a broadly-consented Genome in a Bottle matched tumour-normal pair for somatic benchmarks
- Human genomics
- Cancer research
- PromethION
September 22 2024
Measuring X inactivation skew for X-linked diseases with adaptive nanopore sequencing
- Human genomics
- Clinical research
- Targeted
- Adaptive sampling
- PromethION
- Methylation
September 16 2024
Long-read RNA sequencing of archival tissues reveals novel genes and transcripts associated with clear cell renal cell carcinoma recurrence and immune
- RNA
- cDNA
- Cancer research
- PromethION
- Guppy
September 16 2024
Culture and amplification-free nanopore sequencing for rapid detection of pathogens and antimicrobial resistance genes from urine
- Microbiology
- AMR
- Clinical research
- MinION
- Flongle
- Bacteria
September 16 2024
Long-read DNA and cDNA sequencing identify cancer-predisposing deep intronic variation in tumour-suppressor genes
- Cancer research
- Targeted
- cDNA
- DNA
- PromethION
September 13 2024
Targeted long-read sequencing enriches disease-relevant genomic regions of interest to provide complete Mendelian disease diagnostics
- Human genomics
- Targeted
- Clinical research
- MinION
September 12 2024
Context-Seq: CRISPR-Cas9 targeted nanopore sequencing for transmission dynamics of antimicrobial resistance
- Microbiology
- AMR
- Targeted
- MinION
- MinKNOW
- Guppy
- Bacteria
September 12 2024
ROBIN: a unified nanopore-based sequencing assay integrating real-time, intraoperative methylome classification and next-day comprehensive molecular b
- Cancer research
- Methylation
- PromethION
- MinKNOW
- Targeted
- Adaptive sampling
September 11 2024
Multi-pass, single-molecule nanopore reading of long protein strands
- Protein
- MinION
- MinKNOW
September 11 2024
Scywalker: scalable end-to-end data analysis workflow for long-read single-cell transcriptome sequencing
- Single cell
- Transcriptome
- Transcriptomics
- Workflow
- Scalable
- Long-read
- cDNA
- PromethION
- Guppy
September 10 2024
Harnessing non-standard nucleic acids for highly sensitive icosaplex (20-plex) detection of microbial threats
- Microbiology
- Bacteria
- MinION
- MinKNOW
September 10 2024
Targeted long-read sequencing as a single assay improves diagnosis of spastic-ataxia disorders
- Targeted
- Human genomics
- Clinical research
- Long-read
- Variant calling
- Structural variation
- Splice variation
- PromethION
September 6 2024