Reduced-Representation Methylation Sequencing (RRMS) captures 100% of CpG islands and more

The method allows targeting of important regions in the genome, enabling the genome-wide characterisation of methylation patterns across samples of interest in a cost-effective way.

Download the poster to discover:

  • How adaptive sampling increases coverage of target reads, enabling 8M high-confidence CpGs in key regions of the genome to be called with high accuracy using only a MinION Flow Cell
  • How methylation patterns can be explored between samples to identify high numbers of differentially methylated features and how discarded reads can also be used to call CNV

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