Using nanopore sequencing to screen for aquatic microbial hazards in the lab was too easy, so we are doing it outside

Abstract

We have developed nanopore sequencing capabilities to monitor aquatic environments and detect biological threats, including waterborne pathogens and harmful algae. These assays offer fast and cost-effective methods for accurate characterisation of hazards to humans, animals, and environmental health. It is envisaged that these assays could be used in the field, allowing faster identification of threats and consequently a timelier response. To facilitate this, we are developing mobile capabilities in sample concentration, sample preparation, a mobile sequencing platform, customised assays, and streamlined bioinformatics pipelines. This presentation summarises the developments made, highlighting enhanced capabilities and practical hurdles overcome thus far.