28th October 2023
- In "Network settings and connections", the returned information for the IP address validation has been changed.
- In "Installing and powering on the device", the firewall permissions have been updated.
- In "Changing the default password and hostname", the "Changing the default hostname" has been labelled as Advanced.
- The "Operating system update on GridION" section has been updated with multiple clarifications, updated screenshots and instructions.
May 2023
- Updated screenshots throughout the protocol to be most recent GUI: software release 23.04.X
- In "Flow Cell Check", detailed what the GridION LED colours mean.
26th April 2023
- In "Installing and powering on the device", the power cable instructions have been updated to say: "Connect the power cable to your mains/UPS solution. Use the mains cord supplied, or a suitable approved and rated power cord. Ensure the device is connected to a protective earth mains supply. Turn the power source on."
- In "(Advanced) Updating the software via the Terminal", the reference to port 80 has been removed.
13th March 2023
- In "Operating system update" - "If problems are encountered", a note has been added to say "During the process to blank all of the system’s disks, the following screen will be visible showing either ASRock or ASUS with a scrolling circle. This process may take time to complete and be following by a reboot."
10th March 2023
- In "Device information", the compute specification has been updated to Intel i7-10700K CPU.
- In "Installing and powering on the device", the requirement for Port 80 has been removed
- In "Operating system update" - "If problems are encountered", a new FAQ was added about performing a secure wipe.
- "Downloading the ISO image and burning it to a USB drive" - the link to the ISO image download has been updated. A comment has been added to the Overview to say "These instructions are for users who did not receive a USB drive with the ISO image. If you have received a USB drive, proceed to the next step: "How to boot from USB"."
January 2023
- Updated connection manager screenshot in "Installing and powering on the device" and how users log into MinKNOW software using their Community credentials which now requires the use of OKTA as user authentification.
15th September 2022
- "Downloading the ISO image and burning it to a USB drive": the download link and MD5 hash have been updated. The USB drive specification has been changed from 16 GB to 32 GB.
- "How to boot from USB": a note has been added that once the rebuild process has been completed and the device has had a power cycle, any previous changes to the device password will have defaulted back to the default password.
24th August 2022
Updated to reflect main updates for MinKNOW 22.08 release:
- 'Updating the software' now includes information about update availability and to full power cycle requirement after updates
Other updates:
- 'Flow cell check': the instruction for starting the flow cell check has been updated to say "When you see the flow cell type and flow cell IDs recognised, click 'Start' to begin."
5th May 2022
- "Overview" - the technical specs have been updated: the device weight has been corrected to 14.4 kg, and the functional temperature range for electronics is +5°C to +40°C.
- "Operating system update on GridION": "Completing the restore" - a new instruction has been added: Eject the bootable USB by going to the File Explorer and selecting the Eject icon next to the USB device.
28th March 2022
In "Downloading the ISO image and burning it to a USB drive":
- the Rufus link has been corrected to https://rufus.ie/en/
- the ISO image download link has been updated to include file hash information
In "Completing the restore", the command to restore the hostname has been changed to lowercase `ont-gridion-serial set GXBXXXX`
17th June 2021
The document has been renamed to GridION user manual, with the specific changes below:
- The structure of the document has changed to include the sections "Overview", "Installation", "Pre-sequencing checks and sequencing run", "After completing a sequencing run", "Updating the software" and "Troubleshooting"
- More detailed information and images included to describe GridION components and connections
- Hardware check and flow cell check instructions added
- MinKNOW screenshots have been updated to the MinKNOW v4.3 GUI: Updated login image in the 'Installing and powering on the device' step
9th July 2020
New UI across all devices
Alignment running in MinKNOW
Start of security upgrade - Login
Custom filtering of reads - q-score and read lengths
New barcoding options in the UI
Guppy 4.0 including new basecall models
Admin interface
Update to use Python 3.7
Various improvements to the scripts - new selection criteria at MUX scan, better handling of low-range reads and global flick and drift improvements
ont-vbz-hdf-plugin added as part of the release
Support for upcoming kits and expansion packs - Ligation Sequencing Kit (SQK-LSK110), Native Barcoding Expansion 1-96 (EXP-NBD196) and Rapid Barcoding Kit SQK-RBK096
Added note:
"Please note that only the USB ports on the back of the device are USB 3.0. The ports in the front of the device are USB 2.0, and are not recommended for data transfer."
- Updated check list protocol to v4 Quick Start Guide
- Removed instructions for using reset button
- Updated screen shots due to software changes
- Improved images for port connections