Resource Centre
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Evaluation of a next generation sequencing assay for Hepatitis B antiviral drug resistance on the Oxford Nanopore system
- Infectious disease
- Amplicons
- GridION
- Virus
- AMR
January 15 2025
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Contaminating manufacturing plasmids and disrupted vector genomes present in liver tissue following adeno-associated virus gene therapy
- Biopharma
- Human genomics
- AAV
- PromethION
- MinKNOW
January 14 2025
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Nanopore-based consensus sequencing enables accurate multimodal tumour cell-free DNA profiling
- Cancer research
- cfDNA
- SNVs
- MinION
- PromethION
January 13 2025
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Clinical evaluation of long-read sequencing-based episignature detection in developmental disorders
- Methylation
- Human genomics
- Clinical research
- Whole genome
- Structural variation
- SNVs
January 10 2025
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Cost-effective and flexible preimplantation genetic testing (PGT) using adaptive sampling-based targeted nanopore sequencing (ASTN-seq)
- Human genomics
- Adaptive sampling
- Targeted
- MinION
- MinKNOW
January 10 2025
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Nanopore adaptive sampling accurately detects nucleotide variants and improves the characterisation of large-scale rearrangement
- Human genomics
- Cancer research
- Adaptive sampling
- SNVs
- Q20+
- MinION
January 9 2025
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High prevalence of reverse transcriptase inhibitors associated resistance mutations among people living with HIV on dolutegravir-based antiretroviral
- Virus
- AMR
- Infectious disease
- GridION
January 7 2025
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Diagnostic value of third-generation nanopore sequencing in extrapulmonary tuberculosis
- Infectious disease
- Bacteria
- GridION
January 7 2025
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An improved rapid and sensitive long amplicon method for nanopore-based RSV whole genome sequencing
- Virus
- Infectious disease
- Amplicons
- MinION
January 7 2025
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Genomic diversity and antimicrobial resistance of Vibrio cholerae isolates from Africa: a PulseNet Africa initiative using nanopore sequencing
- Infectious disease
- AMR
- GridION
- Bacteria
- Outbreak
January 4 2025
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Isoform-level discovery, quantification and fusion analysis from single-cell and spatial long-read RNA-seq data with Bambu-Clump
- Single cell
- RNA
- Transcriptomics
- Bioinformatics
- PromethION
January 1 2025
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Nanopore sequencing as a novel method of characterising anorexia nervosa risk loci
- Human genomics
- Neuroscience
- Metabolic
- Targeted
- Adaptive sampling
- Variant calling
December 31 2024
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Nanopore sequencing as a cutting-edge technology for medulloblastoma classification
- Cancer research
- Clinical research
- Flongle
- Methylation
- MinION
- Adaptive sampling
December 28 2024
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Rapid whole genome characterisation of antimicrobial-resistant pathogens using long-read sequencing to identify potential healthcare transmission
- Infectious disease
- Whole genome
- MinION
- Real-time
December 27 2024
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Verkko2: integrating proximity ligation data with long-read De Bruijn graphs for efficient telomere-to-telomere genome assembly, phasing, and scaffold
- Bioinformatics
- Long-read
- Phasing
December 26 2024
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Prognostic importance of direct assignment of parent-of-origin via long-read genome and epigenome sequencing in retinoblastoma
- Cancer research
- Phasing
- Adaptive sampling
- MinION
- Clinical research
December 26 2024
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MrHAMER2: high-accuracy long-read RNA sequencing to decode isoform-specific variation in viral transcripts during latency
- Virus
- Splice variation
- Long-read
- Isoforms
- RNA
- SNVs
December 22 2024
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The utility of long-read sequencing in diagnosing early-onset Parkinson's disease
- Human genomics
- Neuroscience
- Structural variation
- Phasing
- Adaptive sampling
- PromethION
December 19 2024
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Saliva microbiome profiling by full-gene 16S rRNA Oxford Nanopore Technology versus Illumina MiSeq sequencing
- 16S
- Microbiome
- GridION
- MinKNOW
- Bacteria
December 18 2024
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Long-read sequencing of hundreds of diverse brains provides insight into the impact of structural variation on gene expression and DNA methylation
- Human genomics
- Structural variation
- Methylation
- PromethION
December 18 2024