London Calling 2025 - Speakers
Speakers
Check out the line up of speakers at London Calling 2025.
Oxford Nanopore Technologies
Megan L. Noonan
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- Job title
- Institution
- Washington University School of Medicine in St. Louis, USA
- Biography
Megan Noonan is a post-doctoral researcher at Washington University School of Medicine in St. Louis, Division of Nephrology. She completed her PhD in Medical and Molecular Genetics at Indiana University, Indianapolis. Her research aims to uncover novel mechanisms of kidney disease progression via dysregulated alternative splicing. She uses nanopore sequencing to better resolve isoforms for more accurate alternative splicing analysis in bulk and single-cell RNA sequencing datasets.
- Recent publications
Noonan, M.L. et al. Injury-induced FoxM1 expression in mouse kidney drives epithelial proliferation by a cyclin F dependent mechanism. JCI Insight (2024).
DOI: 10.1172/jci.insight.175416Noonan, M.L. et al. Osteocyte Egln1/Phd2 links oxygen sensing and biomineralization via FGF23. Bone Research (2023).
DOI: 10.1038/s41413-022-00241-wNoonan, M.L., Wu, H., and Humphreys, B.D. Long-read sequencing identifies loss of proximal tubule spliceosome gene Srsf7 as a driver of inflammation through alternative splicing. Journal of the American Society of Nephrology 34(11S):842 (2023).
DOI: 10.1681/ASN.20233411S1842a
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