Accelerating cancer research through comprehensive genomic analysis

Overview

In this white paper, you will learn how cancer researchers are using nanopore sequencing to overcome the key challenges associated with short-read sequencing technologies to deliver:

• More complete and contiguous cancer genome assemblies
• Accurate resolution of structural variants and repeat regions
• Rapid identification of fusion genes and full-length transcript isoforms
• Detection of low-abundance cell-free DNA (cfDNA) and circulating tumour DNA (ctDNA)
• Streamlined sequencing of targeted regions
• Detection of epigenetic base modifications from native DNA/RNA — no additional sample prep or sequencing runs required

Read customer case studies describing the detection of a wide variety of genomic variants across a wide range of cancers, including cervical cancer, colorectal cancer, acute myeloid leukaemia, and organoids.