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Dorado basecall server

High-performance commandline basecaller in a client-server configuration as used in MinKNOW. Documentation is included in the package README.md.

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Version: 7.9.8

Release date: 7/16/2025

Approved use: For research use only

  • Functionality from standalone Dorado v0.9.6
  • Model changes: updated to v5.0 DNA models with new 4mC_5mC modification
  • Now supports NVIDIA Blackwell GPUs such as RTX 5090
  • Minimum supported version for Apple Silicon is now macOS 13 (Ventura)
  • Removed support for Intel Macs
  • Strand orientation and UMI detection
  • Trimming low Q-score regions from the end of flicked reads
  • Other output updates, minor changes and bug fixes
Release notesRelease history

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