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Metagenomics and microbial bioinformatics: latest tools and workflows

From metagenomics to full-length 16S ribosomal RNA (rRNA) analysis, Oxford Nanopore sequencing is opening up new opportunities to generate highly complete microbial assemblies, resolve strain-level and within-species diversity, and characterise complex microbial communities at greater resolution than possible with legacy methods.

In this webinar, we explore the latest bioinformatics innovations for analysing amplicon and metagenomic nanopore sequencing datasets. Join Jim Shaw and Gaëtan Benoit as they showcase emerging tools and workflows designed to improve the analysis of complex microbial communities.

Watch Jim present recently developed bioinformatic tools, including Savont and Myloasm, highlighting new approaches for recovering amplicon sequence variant (ASVs) from Oxford Nanopore data, to resolving complete circular genomes and within-species diversity. Gaëtan then discusses the latest advances in NanoMDBG (versions 1.3 and 1.4), focusing on improved assembly quality, error reduction, and computational performance for recovering high-quality metagenome-assembled genomes (MAGs) from large, complex datasets.

Authors: Jim Shaw, Harvard Medical School and Gaëtan Benoit, Pasteur Institute France

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