Resource Centre
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William Jeck: Nanopore sequencing and rapid fusion testing – a ‘killer app’ in molecular pathology
- Oncology
- Nanopore Community Meeting
- Structural variation
December 14 2018
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Whole-genome sequencing with long reads reveals complex structure and origin of structural variation in human genetic variations and somatic mutations in cancer
- Oncology
- Long-read
- Whole genome
- Human genomics
- Cancer research
- SNVs
April 29 2021
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Whole genome assembly of human papillomavirus by nanopore long-read sequencing
- Oncology
- Cancer research
- Clinical research
- Microbiology
- Infectious disease
- MinION
January 4 2022
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In vivo genetic screen identifies a SLC5A3-dependent myo-inositol auxotrophy in acute myeloid leukemia
- Oncology
- Cancer research
- Long-read
- DNA
- GridION
- Clinical research
December 22 2020
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Transcriptome profiling for precision cancer medicine using shallow nanopore cDNA sequencing
- Oncology
- RNA
- Transcriptome
- Gene expression
- Cancer research
- Long-read
February 9 2023
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Transcriptional silencing of ALDH2 in acute myeloid leukemia confers a dependency on Fanconi anemia proteins
- Oncology
- Human genomics
- Cancer research
- Clinical research
- DNA
- Targeted
October 23 2020
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TP53 gene mutation analysis in chronic lymphocytic leukemia by nanopore MinION sequencing
- Oncology
- MinION
- Clinical research
- Cancer research
- Targeted
- Amplicons
October 10 2016
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TEQUILA-seq: a versatile and low-cost method for targeted long-read RNA sequencing
- Oncology
- Splice variation
- MinION
- GridION
- Transcriptome
- Sequence capture
August 8 2023
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A survey of rare epigenetic variation in 23,116 human genomes identifies disease-relevant epivariations and novel CGG expansions
- Oncology
- Methylation
- Epigenetics
- Structural variation
- Long-read
- Clinical research
March 26 2020
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Suberoyl bis-hydroxamic acid reactivates Kaposi’s sarcoma-associated herpesvirus through histone acetylation and induces apoptosis in lymphoma cells
- Oncology
- Clinical research
- MinION
- Transcriptome
- Gene expression
- Virus
September 10 2020
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Case study: solving the parent-of-origin effect in retinoblastoma to determine disease severity
- Oncology
- Adaptive sampling
- Assembly
- Gene expression
- Human genomics
- Long-read
April 4 2025
Single-molecule RNA sequencing reveals IFNγ-induced differential expression of immune escape genes in merkel cell polyomavirus–positive MCC cell lines
- Oncology
- MinION
- RNA
- cDNA
- Gene expression
- Cancer research
November 22 2021
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Single-cell multi-omics reveals elevated plasticity and stem-cell-like blasts relevant to the poor prognosis of KMT2A-rearranged leukemia
- Oncology
- Clinical research
- Cancer research
- Single cell
- Gene fusions
- RNA
December 7 2020
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Simultaneous methylation and chromatin accessibility profiling on breast cancer models
- Oncology
- London Calling
- Cancer research
- DNA
- Long-read
- Epigenetics
May 24 2018
Simultaneous detection and comprehensive analysis of HPV and microbiome status of a cervical liquid-based cytology sample using Nanopore MinION sequencing
- Oncology
- Microbiology
- Virus
- Microbiome
- Metagenomics
- Targeted
December 18 2019
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Short and long-read genome sequencing methodologies for somatic variant detection; genomic analysis of a patient with diffuse large B-cell lymphoma
- Oncology
- Clinical research
- Human genomics
- Cancer research
- Long-read
- Structural variation
March 19 2021
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Robust methylation-based classification of brain tumors using nanopore sequencing
- Oncology
- Methylation
- Human genomics
- Cancer research
- gDNA
- DNA
March 8 2021
Real-time detection of BRAF V600E mutation from archival hairy cell leukemia FFPE tissue by nanopore sequencing
- Oncology
- Clinical research
- Cancer research
- Targeted
- FFPE
- DNA
December 13 2017
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Rapid identification of genomic structural variations with nanopore sequencing enables blood-based cancer monitoring
- Oncology
- Human genomics
- Clinical research
- Cancer research
- DNA
- gDNA
November 15 2019
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Rapid-CNS2: Rapid comprehensive adaptive nanopore-sequencing of CNS tumors, a proof of concept study
- Oncology
- Cancer research
- Real-time
- MinION
- Variant calling
- Clinical research
March 22 2022
