Enabling rapid personalised medicine and real-time antibiotic resistance surveillance for global and advanced heal

Effective sexually transmitted infection (STI) control is challenged by inadequate access to prompt diagnosis and treatment for patients and partners, poor community STI surveillance for targeting public health interventions and changing antimicrobial resistance patterns. Novel field-based detection and sequencing technologies for diagnosis and antimicrobial resistance (AMR) may address these issues by enabling immediate optimised treatment and partner notification, improved capacity to reach those disproportionately affected away from traditional settings of care as well as creating opportunities for monitoring outbreaks. To enable measurable gain from these advances, more thorough understanding of the underlying genomic determinants of AMR is required, while adaptation of technologies to suit clinical and public-health purpose in socially contextualised strategies will be necessary for deployment. This may ultimately give scope for reducing STI transmission and the burden of disease.