Closing unclosable genomes: A new approach combining single-cell Illumina & ONT sequencing
- shared.published_on: September 26 2019
- shared.source: Bigelow SCGC Workshop 2019
Genomics of marine nematode symbionts
- Laxus oneistus and Robbea hypermnestrae, two free-living nematodes (subfamily Stilbonematinae) live in a binary symbiotic association with chemoautotrophic, S-oxidizing Gammaproteobacteria, Candidatus Thiosymbion oneisti and Ca. T. hypermnestrae, respectively
- Each symbiont is attached to the nematode cuticle by one pole as to ensheath its host
Goal: What genomic adaptations do animal-attached bacteria have?
Therefore, we want to unambiguously determine of the complete genetic repertoire.
Challenge: Based on Illumina-based genome drafts, there are repeats up to 7 kb.
