13th March 2023
"Onboarding process":
- A new instruction has been added: "Update to the latest version of MinKNOW for the MinION Mk1C, which supports the latest chemistry, bug fixes and performance enhancements."
- A new instruction has been added: "Navigate to the Device Settings to verify that the date and time are correct. Having the correct time is important to successfully establishing a connection to a network."
"OS update to Ubuntu 18.04 (Bionic) using own microSD card":
- The section has been re-named to "OS update/device recovery using microSD cards"
- Steps 2 and 4 have been updated
13th March 2023
"Onboarding process":
- A new instruction has been added: "Update to the latest version of MinKNOW for the MinION Mk1C, which supports the latest chemistry, bug fixes and performance enhancements."
- A new instruction has been added: "Navigate to the Device Settings to verify that the date and time are correct. Having the correct time is important to successfully establishing a connection to a network."
"OS update to Ubuntu 18.04 (Bionic) using own microSD card":
- The section has been re-named to "OS update/device recovery using microSD cards"
- Steps 2 and 4 have been updated
5th January 2023
- "(Advanced) Connecting by the command-line" has been updated with new instructions for connecting to the MinION Mk1C using SSH or the Terminal
- A new section has been added: "Data transfer via SFTP"
5th January 2023
- "(Advanced) Connecting by the command-line" has been updated with new instructions for connecting to the MinION Mk1C using SSH or the Terminal
- A new section has been added: "Data transfer via SFTP"
24th August 2022
Updated to reflect main updates for MinKNOW 22.08 release:
- 'Installation' section now includes an 'Onboarding process' step, documenting the set up of new MinION Mk1C devices
- 'Updating the software' includes update availability
Other updates:
- 'Flow cell check': the instruction for starting the flow cell check has been updated to say "When you see the flow cell type and flow cell IDs recognised, click 'Start' to begin."
11th August 2022
- In "Device information", the operating temperature has been corrected to: "Designed to sequence at +10°C to +30°C / Functional range of electronics +5°C to +40°C".
- In "(Advanced) Connecting by the command-line", the instructions for connecting to the Mk1C via SSH have been updated.
- In "If your Mk1C does not boot from microSD card", the maximum Mk1C serial number has been updated to "Some Mk1C devices with serial numbers MC-110999 or lower may not be able to recognise the microSD card with OS updates..."
20th June 2022
- In "OS update to Ubuntu 18.04 (Bionic) using own microSD card", a clarification has been added to Step 3: "Select "Factory Reset" to re-image the device with the software on the microSD card." Also, two new steps have been added at the end: one is "Completing your OS update", and the second to instruct users to update the signing key on their device.
- In "Updating the software", a new section has been added: "Updating the signing key to update MinKNOW (IMPORTANT)".
- In "Network settings and connection" - "To connect the MinION Mk1C router to a macOS device", an explanation has been added at the bottom for how to SSH into the device using DNS, mDNS, and the IP address.
- In "(Advanced) Updating the software via SSH", a new installation command has been added: sudo apt install ont-mk1c-release .
- Minor error/typo corrections.
14th April 2022
- In "Updating the software", a new step has been added: "OS update to Ubuntu 18.04 (Bionic) using own microSD card"
- In "Troubleshooting", a new step has been added: "If your Mk1C does not boot from microSD card"
23rd July 2021
In "Network settings and connection", instructions have been added for how to connect the MinION Mk1C Wi-Fi router to a Windows, macOS and Linux devices.
16 June 2021
- All screenshots have been updated to the updated MinKNOW 4.3 GUI.
- Added section to 'Pre-Sequencing checks and sequencing run' to include 'hardware check'
- Updated 'sequencing on the MinION Mk1C' to 'Sequencing and monitoring the experiment' which has added information with a link to the MinKNOW protocol on how to set up a sequencing experiment and monitoring the run.
- In 'Installtion: Powering the device', we have updated the login screenshot to the new MinKNOG GUI
- In both 'Hardware check' sections, we have updated the login screenshot
- In 'Updating the software: Updating the software via the UI', additional steps have been included to power off the device and back on again before checking version number.
- In 'Troubleshooting: Export logs' has been updated to include additional information on where to find the exported logs in the file manager.
10th March 2021
- In the "Starting a sequencing run" section, instructions have been added to enable adaptive sampling for the initial MinION Mk1C release.
4th March 2021
- Updated 'General connection information' to encourage use of GUI. Moved 'Connection to device' to after 'Power'.
- Removed sections including 'Connection by Ethernet' for all OS and 'Connection by Wifi' for all OS as this is completed on the GUI on Host settings.
- Changed Admin Interface to 'Host settings'
- Updated 'Data transfer, output and logs' to use the File Manager GUI rather than command line.
- Updated instructions for generating a run report in 'Starting a sequencing run'
9th July 2020
New UI across all devices
Alignment running in MinKNOW
Start of security upgrade - Login
Custom filtering of reads - q-score and read lengths
New barcoding options in the UI
Guppy 4.0 including new basecall models
Admin interface
Update to use Python 3.7
Various improvements to the scripts - new selection criteria at MUX scan, better handling of low-range reads and global flick and drift improvements
ont-vbz-hdf-plugin added as part of the release
Support for upcoming kits and expansion packs - Ligation Sequencing Kit (SQK-LSK110), Native Barcoding Expansion 1-96 (EXP-NBD196) and Rapid Barcoding Kit SQK-RBK096