Software downloads
Dorado
High-performance, easy-to-use commandline basecaller for Nanopore data. Developer release for evaluation of new features. For information about the Dorado project, see https://github.com/nanoporetech/dorado.
Select your operating system
Dorado documentation
For more detailed advice, documentation and installation guides for DoradoVersion: 1.1.1
Release date: 8/13/2025
Approved use: For research use only
- Update to improved 5mC_5hmC and 5mCG_5hmCG modified base models for V5.2 models. These new models improve modified base calling for all-context 5mC_5hmC. Note that there is minimal benefit to re-basecalling datasets already called with the v5.2.0 v1 CpG context models, as there will be little or no change to the results.
- Fix a runtime error when modified base calling on Hopper GPUs.
- Add ch and PU tags to FastQ headers.
- Fix missing metadata in output folder and file names for dorado align command.
Nanopore Community
The Nanopore Community contains many useful resources, including:
Protocols
Build or select a protocol using our range of tools.
Bioinformatics
Build or select a protocol using our range of tools.
Extraction methods
Detailed extraction protocols and specific recommendations are provided for various tissue types.
