We have sequenced 20 pairs of Korean colon cancer patients using cDNA PCR Nanopore technology to identify colon cancer specific novel biomarkers that can be used for clinical usage.
We attempted to identify novel isoform, non-coding RNAs and fusion genes. Some candidates that were found were shown to have potential to be new colon cancer diagnostic biomarkers.
By using more precise and accurate data to detect such biomarkers, we want not only to be able to use them for clinical usage, but also to further propose a new molecular mechanism to better understand colon cancer tumorigenesis using Nanopore data.
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